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Details on Person STING dimerization
Class:Id Reaction:3134800 _displayName STING dimerization _doRelease TRUE _timestamp 2022-02-14 06:55:52 authored [InstanceEdit:3065946] Shamovsky, V, 2013-02-06 compartment [Compartment:12045] endoplasmic reticulum membrane created [InstanceEdit:3134801] Shamovsky, V, 2013-02-13 edited [InstanceEdit:3465604] Shamovsky, V, 2013-05-17 input [EntityWithAccessionedSequence:1834940] STING [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:1834940] STING [endoplasmic reticulum membrane] [Homo sapiens] isChimeric FALSE literatureReference [LiteratureReference:2395975] Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding [LiteratureReference:2408472] Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system modified [InstanceEdit:3134977] Shamovsky, V, 2013-02-13 [InstanceEdit:3248025] Shamovsky, V, 2013-04-05 [InstanceEdit:3249352] Shamovsky, V, 2013-04-08 [InstanceEdit:3249401] Shamovsky, V, 2013-04-09 [InstanceEdit:3465584] Shamovsky, V, 2013-05-17 [InstanceEdit:3465599] Shamovsky, V, 2013-05-17 [InstanceEdit:3465600] Shamovsky, V, 2013-05-17 [InstanceEdit:3465604] Shamovsky, V, 2013-05-17 [InstanceEdit:3508920] Shamovsky, V, 2013-05-20 [InstanceEdit:3597629] Shamovsky, V, 2013-05-21 [InstanceEdit:9711024] Shamovsky, Veronica, 2021-01-07 [InstanceEdit:9716571] Shamovsky, Veronica, 2021-02-22 [InstanceEdit:9730875] Shamovsky, Veronica, 2021-05-11 [InstanceEdit:9731191] Shamovsky, Veronica, 2021-05-14 [InstanceEdit:9764238] Stephan, Ralf, 2022-02-10 [InstanceEdit:9764714] Shamovsky, Veronica, 2022-02-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name STING dimerization output [Complex:2395989] STING:STING [endoplasmic reticulum membrane] [Homo sapiens] precedingEvent
regulatedBy [PositiveRegulation:9711023] Positive regulation by 'K63polyUb-STING [endoplasmic reticulum membrane]' regulationReference [RegulationReference:9711020] Positive regulation by 'K63polyUb-STING [endoplasmic reticulum membrane]' TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination releaseDate 2013-06-11 reviewed [InstanceEdit:3110284] D'Eustachio, P, 2013-02-11 [InstanceEdit:9731189] Jin, Lei, 2021-05-14 [InstanceEdit:9731190] Wu, Jiaxi, 2021-05-14 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:3654174] R-HSA-3134800.5 summation [Summation:3249348] STING dimerization is essential for the induction of IFN res... (hasEvent) [Pathway:1834941] STING mediated induction of host immune responses [Homo sapiens] (precedingEvent) [Reaction:1834939] STING recruits TBK1 and IRF3 [Homo sapiens] [BlackBoxEvent:2396009] STING binds c-di-GMP [Homo sapiens] [BlackBoxEvent:3244643] STING binds cyclic GMP-AMP [Homo sapiens] [Reaction:3249378] STING recruits TBK1 and STAT6 [Homo sapiens] (updatedInstance) [_UpdateTracker:9776306] Update Tracker - [Reaction:3134800] STING dimerization - v76:[addRegulator, modifyText]
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No pathways have been reviewed or authored by STING dimerization (3134800)
