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Details on Person cGMP [cytosol]
| Class:Id | SimpleEntity:30991 |
| _displayName | cGMP [cytosol] |
| _timestamp | 2025-11-10 09:30:50 |
| compartment | [Compartment:70101] cytosol |
| crossReference | [DatabaseIdentifier:30992] COMPOUND:C00942 |
| modified | [InstanceEdit:113650] Schmidt, EE, 2004-06-11 05:29:07 [InstanceEdit:2514885] Jassal, B, 2012-10-11 [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9619952] Wu, G, 2018-09-19 [InstanceEdit:9971695] Stephan, Ralf, 2025-11-10 |
| name | cGMP Guanosine 3',5'-cyclic monophosphate 3',5'-cyclic GMP Guanosine 3',5'-cyclic phosphate Cyclic GMP |
| referenceEntity | [ReferenceMolecule:9971693] 3',5'-cyclic GMP(1-) [ChEBI:57746] |
| stableIdentifier | [StableIdentifier:1112128] R-ALL-30991.4 |
| (hasComponent) | [Complex:74008] open cGMP-gated ion channel [plasma membrane] [Bos taurus] [Complex:74011] cGMP:CNG channel [plasma membrane] [Homo sapiens] [Complex:418378] Activated cGMP-dependent protein kinase (PKGs) [cytosol] [Homo sapiens] [Complex:427305] Activated cGMP-dependent protein kinase (PKG) [cytosol] [Homarus americanus] [Complex:4551452] Prkg homodimer:cGMP [cytosol] [Mus musculus] [Complex:4551456] PRKG homodimer:cGMP [cytosol] [Homo sapiens] [Complex:9653485] PRKG2 dimer:cGMP [cytosol] [Homo sapiens] |
| (hasMember) | [DefinedSet:561078] OAT1,2,3 substrates [cytosol] [DefinedSet:9974597] SLC22A7 end. metabolite cargo [cytosol] |
| (input) | [Reaction:74031] cGMP binds CNG channel to form cGMP:CNG channel [Homo sapiens] [Reaction:74059] PDE6 hydrolyses cGMP to GMP [Homo sapiens] [Reaction:418451] cGMP stimulates Protein Kinase G [Homo sapiens] [Reaction:418456] cGMP is degraded by PDEs [Homo sapiens] [Reaction:427308] cGMP stimulates Protein Kinase G [Homarus americanus] [Reaction:4086392] PDE6 hydrolyses cGMP to GMP [Homo sapiens] [Reaction:4551446] Prkg is activated upon cGMP binding [Mus musculus] [Reaction:4551453] PRKG is activated by binding to high levels of cGMP in the absence of WNT signaling [Homo sapiens] [Reaction:9708129] PDE5A dimer hydrolyses cGMP to GMP [Homo sapiens] |
| (output) | [Reaction:74885] GUCYs converts GTP to cGMP [Homo sapiens] [Reaction:392152] Soluble guanylate cyclase converts GTP to cGMP [Homo sapiens] [Reaction:427288] Soluble guanylate cyclase converts GTP to cGMP [Rattus norvegicus] [Reaction:2514865] cGMP dissociates from CNG channels [Homo sapiens] |
| (regulator) | [NegativeRegulation:9620126] Negative regulation by 'cGMP [cytosol]' |
| (updatedInstance) | [_UpdateTracker:9873384] Update Tracker - [SimpleEntity:30991] cGMP [cytosol] - v43:[addName] [_UpdateTracker:9890842] Update Tracker - [SimpleEntity:30991] cGMP [cytosol] - v52:[modifyName] [_UpdateTracker:9972775] Update Tracker - [SimpleEntity:30991] cGMP [cytosol] - v95:[add_removeReferenceEntity] |
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No pathways have been reviewed or authored by cGMP [cytosol] (30991)