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Details on Person Extracellular BTD hydrolyses BCTN

Class:Id	Reaction:3076905
_displayName	Extracellular BTD hydrolyses BCTN
_doRelease	TRUE
_timestamp	2013-08-15 14:24:24
authored	[InstanceEdit:3076883] Jassal, B, 2013-02-07
catalystActivity	[CatalystActivity:3076906] biotinidase activity of BTD [extracellular region]
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:3076883] Jassal, B, 2013-02-07
edited	[InstanceEdit:3076883] Jassal, B, 2013-02-07
input	[SimpleEntity:3076887] BCTN [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:3076892] Human serum biotinidase. cDNA cloning, sequence, and characterization [LiteratureReference:3282866] Biotinidase deficiency: the enzymatic defect in late-onset multiple carboxylase deficiency [LiteratureReference:4167533] Evolutionary conservation of biotinidase: implications for the enzyme's structure and subcellular localization
modified	[InstanceEdit:3206860] Jassal, B, 2013-03-01 [InstanceEdit:3282867] Jassal, B, 2013-04-12 [InstanceEdit:3288226] Jassal, Bijay, 2013-04-15 [InstanceEdit:4167504] Jassal, B, 2013-08-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Extracellular BTD hydrolyses BCTN
output	[SimpleEntity:199238] Btn [extracellular region] [SimpleEntity:351991] L-Lys [extracellular region]
precedingEvent	[BlackBoxEvent:3076881] BCTN translocates to extracellular region [Homo sapiens] [BlackBoxEvent:3065958] An unknown protease degrades ACACA [Homo sapiens] [BlackBoxEvent:3065959] An unknown protease degrades hCBXs [Homo sapiens]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3288227] D'Eustachio, P, 2013-04-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654186] R-HSA-3076905.2
summation	[Summation:3076898] Human biotinidase (BTD, EC 3.5.1.12) (Cole et al. 1994) cata...
(hasEvent)	[Pathway:196780] Biotin transport and metabolism [Homo sapiens]
(normalReaction)	[FailedReaction:3325540] Defective extracellular BTD does not hydrolyse BCTN [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787232] Update Tracker - [Reaction:3076905] Extracellular BTD hydrolyses BCTN - v46:[add_removeLiteratureReference, modifyText]
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No pathways have been reviewed or authored by Extracellular BTD hydrolyses BCTN (3076905)