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Details on Person monoSUMO1-K182-MDM2 [nucleoplasm]

Class:IdEntityWithAccessionedSequence:3000408
_displayNamemonoSUMO1-K182-MDM2 [nucleoplasm]
_timestamp2022-01-19 16:28:14
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:3000365] May, B, 2013-01-26
endCoordinate491
hasModifiedResidue[GroupModifiedResidue:3000395] sumoylated lysine (monoSUMO1 [nucleoplasm]) at 182
literatureReference[LiteratureReference:2997695] SUMO E3 ligase activity of TRIM proteins
[LiteratureReference:3000412] Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes
modified[InstanceEdit:3632837] May, B, 2013-05-26
[InstanceEdit:4663810] May, B, 2013-10-06
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9762279] May, Bruce, 2022-01-19
namemonoSUMO1-K182-MDM2
SUMO1 N-glycyl-lys MDM2
E3 ubiquitin-protein ligase Mdm2 ecNumber6.3.2.-/ecNumber
MDM2_HUMAN
referenceEntity[ReferenceGeneProduct:95018] UniProt:Q00987 MDM2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8898944] R-HSA-3000408.2
startCoordinate1
(output)[Reaction:3000434] PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 [Homo sapiens]
[Reaction:5228523] RANBP2 SUMOylates MDM2 with SUMO1 [Homo sapiens]
(replacementInstances)[_Deleted:9762697] Deletion of instance: 3000446
[_Deleted:9762729] Deletion of instance: 3730855
(updatedInstance)[_UpdateTracker:9903278] Update Tracker - [EntityWithAccessionedSequence:3000408] monoSUMO1-K182-MDM2 [nucleoplasm] - v80:[modifyName]
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No pathways have been reviewed or authored by monoSUMO1-K182-MDM2 [nucleoplasm] (3000408)