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Details on Person RANBP2 SUMOylates SP100 with SUMO1

Class:IdReaction:3000399
_displayNameRANBP2 SUMOylates SP100 with SUMO1
_doReleaseTRUE
_timestamp2022-01-19 16:44:55
authored[InstanceEdit:2997736] May, B, 2013-01-23
catalystActivity[CatalystActivity:3000418] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope]
catalystActivityReference[CatalystActivityReference:9644133] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection
compartment[Compartment:7660] nucleoplasm
[Compartment:13231] nuclear envelope
created[InstanceEdit:3000365] May, B, 2013-01-26
edited[InstanceEdit:2997736] May, B, 2013-01-23
input[EntityWithAccessionedSequence:1031705] SP100 [nucleoplasm] [Homo sapiens]
[Complex:2993783] SUMO1:C93-UBE2I [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:3000459] Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection
[LiteratureReference:3000453] The nucleoporin RanBP2 has SUMO1 E3 ligase activity
[LiteratureReference:4085361] Ubc9 sumoylation regulates SUMO target discrimination
modified[InstanceEdit:3006236] May, B, 2013-01-29
[InstanceEdit:3065680] May, B, 2013-02-06
[InstanceEdit:3730795] May, B, 2013-06-15
[InstanceEdit:4663810] May, B, 2013-10-06
[InstanceEdit:5655646] May, Bruce, 2014-12-08
[InstanceEdit:5677004] May, Bruce, 2015-02-21
[InstanceEdit:9644134] May, Bruce, 2019-04-08
[InstanceEdit:9762281] May, Bruce, 2022-01-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRANBP2 SUMOylates SP100 with SUMO1
Conjugation of SUMO1 to SP100
output[EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:3000382] monoSUMO1-K297-SP100 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2015-03-19
reviewed[InstanceEdit:5677000] Ferrari, Stefano, 2015-02-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5679678] R-HSA-3000399.4
summation[Summation:4663808] RANBP2 SUMOylates SP100 with SUMO1 at lysine-297 (Pichler et...
(hasEvent)[Pathway:3108214] SUMOylation of DNA damage response and repair proteins [Homo sapiens]
(updatedInstance)[_UpdateTracker:9774962] Update Tracker - [Reaction:3000399] RANBP2 SUMOylates SP100 with SUMO1 - v80:[add_removeOutput]
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No pathways have been reviewed or authored by RANBP2 SUMOylates SP100 with SUMO1 (3000399)