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Details on Person PLK1 phosphorylates BORA
Class:Id Reaction:3000327
_displayName PLK1 phosphorylates BORA
_doRelease TRUE
_timestamp 2013-09-05 11:44:50
authored [InstanceEdit:3004457] Orlic-Milacic, M, 2013-01-28
catalystActivity [CatalystActivity:3000326] protein serine/threonine kinase activity of p-7S,2T-BORA:p-T210-PLK1 [cytosol]
catalystActivityReference [CatalystActivityReference:9643264] protein serine/threonine kinase activity of p-S252-BORA:p-T210-PLK1 [cytosol] Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression
compartment [Compartment:70101] cytosol
created [InstanceEdit:3000329] Orlic-Milacic, M, 2013-01-24
edited [InstanceEdit:3006289] Orlic-Milacic, M, 2013-01-29
input [Complex:3000305] p-7S,2T-BORA:p-T210-PLK1 [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric FALSE
literatureReference [LiteratureReference:3000332] Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression
modified [InstanceEdit:3002853] Orlic-Milacic, M, 2013-01-28 [InstanceEdit:4410469] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4410475] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4410476] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4410477] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name PLK1 phosphorylates BORA
output [EntityWithAccessionedSequence:3000318] p-T210-PLK1 [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [EntityWithAccessionedSequence:3000330] p-8S,3T-BORA [cytosol] [Homo sapiens]
precedingEvent
releaseDate 2013-09-18
reviewed [InstanceEdit:4410473] Bruinsma, Wytse, 2013-08-21
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:4545168] R-HSA-3000327.3
summation [Summation:3002842] PLK1 phosphorylates BORA on serine residue S497 and threonin...
(hasEvent) [Pathway:2565942] Regulation of PLK1 Activity at G2/M Transition [Homo sapiens]
(precedingEvent) [NegativePrecedingEvent:9764024] Futile Cycle: PLK1 phosphorylates BORA [NegativePrecedingEvent:9764028] Futile Cycle: PLK1 phosphorylates BORA [NegativePrecedingEvent:9764029] Futile Cycle: PLK1 phosphorylates BORA [NegativePrecedingEvent:9764034] Futile Cycle: PLK1 phosphorylates BORA [Reaction:156682] PLK1 phosphorylates NUDC [Homo sapiens] [Reaction:1638803] Phosphorylation of cohesin by PLK1 at centromeres [Homo sapiens] [Reaction:2172194] Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65) [Homo sapiens] [Reaction:2466068] Phosphorylation of cohesin by PLK1 at chromosomal arms [Homo sapiens] [Reaction:2984226] PLK1 phosphorylates NEK9 [Homo sapiens] [Reaction:3000339] Phosphorylated BORA binds SCF-beta-TrCp1/2 [Homo sapiens]
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