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Details on Person Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry

Class:IdLiteratureReference:3000320
_displayNameBora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry
_timestamp2013-01-24 20:22:04
author[Person:3000306] Seki, Akiko
[Person:3000311] Coppinger, Judith A
[Person:3000309] Jang, Chang-Young
[Person:3000308] Yates, John R
[Person:3000314] Fang, Guowei
created[InstanceEdit:3000317] Orlic-Milacic, M, 2013-01-24
journalScience
pages1655-8
pubMedIdentifier18566290
titleBora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry
volume320
year2008
(literatureReference)[Pathway:2565942] Regulation of PLK1 Activity at G2/M Transition [Homo sapiens]
[Reaction:3000307] BORA binds PLK1 [Homo sapiens]
[Reaction:3000310] AURKA phosphorylates PLK1 [Homo sapiens]
[Reaction:3000319] BORA binds PLK1 and AURKA [Homo sapiens]
[Complex:3000315] p-S252-BORA:PLK1 [cytosol] [Homo sapiens]
[CatalystActivityReference:9643682] protein serine/threonine kinase activity of Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry
[CatalystActivityReference:9643708] protein serine/threonine kinase activity of p-T288-AURKA:TPX2 [nucleoplasm] Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry
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