Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person AURKA phosphorylates PLK1

Class:Id	Reaction:3000310
_displayName	AURKA phosphorylates PLK1
_doRelease	TRUE
_timestamp	2013-09-05 11:49:32
authored	[InstanceEdit:3004457] Orlic-Milacic, M, 2013-01-28
catalystActivity	[CatalystActivity:3000312] protein serine/threonine kinase activity of Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643682] protein serine/threonine kinase activity of Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3000317] Orlic-Milacic, M, 2013-01-24
edited	[InstanceEdit:3006289] Orlic-Milacic, M, 2013-01-29
input	[Complex:3000313] Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:3002841] Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery [LiteratureReference:3000320] Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry [LiteratureReference:3002857] Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase
modified	[InstanceEdit:3000334] Orlic-Milacic, M, 2013-01-24 [InstanceEdit:3002853] Orlic-Milacic, M, 2013-01-28 [InstanceEdit:3002861] Orlic-Milacic, M, 2013-01-28 [InstanceEdit:4410469] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4410475] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4410476] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4410477] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AURKA phosphorylates PLK1
output	[Complex:3000305] p-7S,2T-BORA:p-T210-PLK1 [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [Complex:3000302] Centrosome:p-T288-AURKA [cytosol] [Homo sapiens]
precedingEvent	[Reaction:3000319] BORA binds PLK1 and AURKA [Homo sapiens] [Reaction:4086410] CCNB:CDK1 phosphorylates BORA [Homo sapiens] [Reaction:2574840] AJUBA facilitates AURKA autophosphorylation [Homo sapiens] [BlackBoxEvent:4088305] FOXM1 stimulates PLK1 transcription [Homo sapiens] [Reaction:9929532] CCNA:CDK1 phosphorylates BORA [Homo sapiens]
releaseDate	2013-09-18
reviewed	[InstanceEdit:4410473] Bruinsma, Wytse, 2013-08-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545251] R-HSA-3000310.3
summation	[Summation:3002845] AURKA (Aurora A kinase) phosphorylates PLK1 on threonine res...
(hasEvent)	[Pathway:2565942] Regulation of PLK1 Activity at G2/M Transition [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9764016] Futile Cycle: AURKA phosphorylates PLK1 [Reaction:2562526] PLK1 phosphorylates OPTN [Homo sapiens] [Reaction:3000327] PLK1 phosphorylates BORA [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by AURKA phosphorylates PLK1 (3000310)