Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person CD320 binds extracellular TCN2:RCbl

Class:Id	Reaction:3000122
_displayName	CD320 binds extracellular TCN2:RCbl
_doRelease	TRUE
_timestamp	2022-02-14 15:46:55
authored	[InstanceEdit:3000082] Jassal, Bijay, 2013-01-24
catalystActivity	[CatalystActivity:3000088] cargo receptor activity of CD320 [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9758899] cargo receptor activity of CD320 [plasma membrane] The binding properties of the human receptor for the cellular uptake of vitamin B12
compartment	[Compartment:984] extracellular region [Compartment:74700] endosome membrane [Compartment:17940] endosome
created	[InstanceEdit:3000082] Jassal, Bijay, 2013-01-24
edited	[InstanceEdit:3000082] Jassal, Bijay, 2013-01-24
input	[EntityWithAccessionedSequence:2980909] CD320 [plasma membrane] [Homo sapiens] [Complex:9759429] TCN2:RCbl [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3000080] The binding properties of the human receptor for the cellular uptake of vitamin B12 [LiteratureReference:3000116] The protein and the gene encoding the receptor for the cellular uptake of transcobalamin-bound cobalamin [LiteratureReference:3000076] Positive newborn screen for methylmalonic aciduria identifies the first mutation in TCblR/CD320, the gene for cellular uptake of transcobalamin-bound vitamin B(12)
modified	[InstanceEdit:3000139] Jassal, Bijay, 2013-01-24 [InstanceEdit:3132777] Jassal, Bijay, 2013-02-13 [InstanceEdit:3162927] Jassal, Bijay, 2013-02-21 [InstanceEdit:3162930] Jassal, Bijay, 2013-02-21 [InstanceEdit:3288226] Jassal, Bijay, 2013-04-15 [InstanceEdit:3968436] Jassal, Bijay, 2013-07-24 [InstanceEdit:9758898] D'Eustachio, Peter, 2021-11-26 [InstanceEdit:9759431] D'Eustachio, Peter, 2021-12-03 [InstanceEdit:9764875] D'Eustachio, Peter, 2022-02-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CD320 binds extracellular TCN2:RCbl
negativePrecedingEvent	[NegativePrecedingEvent:9764872] Futile Cycle: CD320-mediated TCN2:RCbl uptake and delivery to lysosome
output	[Complex:3000089] TCN2:RCbl:CD320 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:3000074] TCN2 binds RCbl in the circulation [Homo sapiens] [Reaction:3095901] ABCC1 transports cytosolic RCbl to extracellular region [Homo sapiens]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3288227] D'Eustachio, P, 2013-04-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654201] R-HSA-3000122.3
summation	[Summation:3000094] The ubiquitously expressed CD320 antigen (CD320 aka transcob...
(hasEvent)	[Pathway:9758890] Transport of RCbl within the body [Homo sapiens]
(normalReaction)	[FailedReaction:3325546] Defective CD320 does not transport extracellular TCII:Cbl to endosome [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:3000112] CD320-mediated TCN2:RCbl uptake and delivery to lysosome [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775146] Update Tracker - [Reaction:3000122] CD320 binds extracellular TCN2:RCbl - v80:[add_removeInput, modifyText] [_UpdateTracker:9786252] Update Tracker - [Reaction:3000122] CD320 binds extracellular TCN2:RCbl - v50:[modifyText] [_UpdateTracker:9786997] Update Tracker - [Reaction:3000122] CD320 binds extracellular TCN2:RCbl - v46:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by CD320 binds extracellular TCN2:RCbl (3000122)