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Details on Person NEK9 phosphorylates NEK6/NEK7

Class:IdReaction:2984258
_displayNameNEK9 phosphorylates NEK6/NEK7
_doReleaseTRUE
_timestamp2013-02-28 10:50:11
authored[InstanceEdit:2995320] Orlic-Milacic, M, 2013-01-21
catalystActivity[CatalystActivity:2984249] protein serine/threonine kinase activity of p-3S,2T-NEK9:NEK6/NEK7 [cytosol]
catalystActivityReference[CatalystActivityReference:9643951] protein serine/threonine kinase activity of p-3S,2T-NEK9:NEK6/NEK7 [cytosol] A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases
compartment[Compartment:70101] cytosol
created[InstanceEdit:2984245] Orlic-Milacic, M, 2013-01-16
edited[InstanceEdit:2997529] Gillespie, ME, 2013-01-23
input[SimpleEntity:113592] ATP [cytosol]
[Complex:2980721] p-3S,2T-NEK9:NEK6/NEK7 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:2980712] A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases
[LiteratureReference:2984257] An autoinhibitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9
modified[InstanceEdit:2984263] Orlic-Milacic, M, 2013-01-16
[InstanceEdit:3132747] Orlic-Milacic, M, 2013-02-12
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNEK9 phosphorylates NEK6/NEK7
output[SimpleEntity:29370] ADP [cytosol]
[Complex:2984255] p-3S,2T-NEK9: p-S206-NEK6/ p-S195-NEK7 [cytosol] [Homo sapiens]
precedingEvent
releaseDate2013-03-12
reviewed[InstanceEdit:3132746] Avruch, Joseph, 2013-02-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3200288] R-HSA-2984258.3
summation[Summation:2984261] NEK9, activated by CDK1- and PLK1-mediated phosphorylation, ...
(hasEvent)[Pathway:2980767] Activation of NIMA Kinases NEK9, NEK6, NEK7 [Homo sapiens]
(precedingEvent)[Reaction:2990880] NEK6/NEK7 phosphorylates NUP98 [Homo sapiens]
[Reaction:9648089] NEK6 and NEK7 phosphorylate EML4 [Homo sapiens]
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