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Details on Person POU5F1 (OCT4), SOX2, NANOG bind the FOXD3 promoter

Class:Id	Reaction:2972964
_displayName	POU5F1 (OCT4), SOX2, NANOG bind the FOXD3 promoter
_doRelease	TRUE
_timestamp	2014-11-20 02:56:06
authored	[InstanceEdit:2901807] May, B, 2013-01-03
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:2972945] D'Eustachio, P, 2013-01-06
edited	[InstanceEdit:2901807] May, B, 2013-01-03
input	[EntityWithAccessionedSequence:2888992] FOXD3 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:452586] NANOG [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:452472] POU5F1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:452271] SOX2 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells [LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [LiteratureReference:5246719] Human DNA methylomes at base resolution show widespread epigenomic differences [LiteratureReference:5250252] Transposable elements have rewired the core regulatory network of human embryonic stem cells
modified	[InstanceEdit:3108239] May, B, 2013-02-10 [InstanceEdit:3165216] May, B, 2013-02-22 [InstanceEdit:4411347] May, B, 2013-08-23 [InstanceEdit:4420242] May, B, 2013-08-31 [InstanceEdit:5159238] D'Eustachio, P, 2013-11-22 [InstanceEdit:5250254] May, B, 2014-01-24 [InstanceEdit:5250255] May, B, 2014-01-24 [InstanceEdit:5251384] May, B, 2014-02-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	POU5F1 (OCT4), SOX2, NANOG bind the FOXD3 promoter
output	[Complex:2889032] POU5F1:SOX2:NANOG:FOXD3 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:452838] Expression of NANOG [Homo sapiens] [Reaction:480204] POU5F1 (OCT4), SOX2, NANOG, KLF4, PBX1, SMAD2 bind the NANOG promoter [Homo sapiens] [BlackBoxEvent:452894] Expression of SOX2 [Homo sapiens] [Reaction:480685] POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter [Homo sapiens] [BlackBoxEvent:2889036] Translation of OCT4 mRNA [Homo sapiens] [Reaction:500366] LIN28 binds POU5F1 (OCT4) mRNA [Homo sapiens]
releaseDate	2014-03-12
reviewed	[InstanceEdit:5246708] Wang, Jianlong, 2014-01-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645144] R-HSA-2972964.2
summation	[Summation:2972910] The FOXD3 gene is bound by POU5F1 (OCT4) (Boyer et al. 2005,...
(hasEvent)	[Pathway:2892247] POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:452750] Expression of FOXD3 [Homo sapiens]
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No pathways have been reviewed or authored by POU5F1 (OCT4), SOX2, NANOG bind the FOXD3 promoter (2972964)