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Details on Person LACT [cytosol]
| Class:Id | SimpleEntity:29708 |
| _displayName | LACT [cytosol] |
| _timestamp | 2024-02-21 17:02:59 |
| compartment | [Compartment:70101] cytosol |
| crossReference | [DatabaseIdentifier:29709] COMPOUND:C00186 |
| modified | [InstanceEdit:113469] Schmidt, EE, 2004-05-17 12:03:06 [InstanceEdit:2537470] Wu, G, 2012-10-26 [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9619952] Wu, G, 2018-09-19 [InstanceEdit:9861969] Stephan, Ralf, 2024-02-21 [InstanceEdit:9989189] Weiser, Joel, 2026-05-17 |
| name | LACT (S)-lactate (S)-Lactate (S)-lactic acid L-Lactate L-Lactic acid |
| referenceEntity | [ReferenceMolecule:5317527] (S)-lactate [ChEBI:16651] |
| stableIdentifier | [StableIdentifier:366693] R-ALL-29708.4 |
| (hasMember) | [DefinedSet:429748] monocarboxylates transported by SLC5A8 [cytosol] [DefinedSet:433686] MCT substrates [cytosol] [DefinedSet:8876304] LACT, PYR, NCA [cytosol] |
| (input) | [Reaction:70510] LDH tetramer oxidises LACT to PYR [Homo sapiens] [Reaction:372903] lactate + NAD+ <=> pyruvate + NADH + H+ [Gallus gallus] [Reaction:373875] BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region [Homo sapiens] [Reaction:373889] lactate + H+ [cytosol] <=> lactate + H+ [extracellular] [Gallus gallus] [Reaction:561253] SLC22A12 exchanges extracellular urate for cytosolic LACT [Homo sapiens] [FailedReaction:5625210] Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT [Homo sapiens] |
| (output) | [Reaction:71849] LDH tetramer reduces PYR to LACT [Homo sapiens] [Reaction:372910] pyruvate + NADH + H+ <=> lactate + NAD+ [Gallus gallus] [Reaction:373867] BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol [Homo sapiens] [Reaction:373887] lactate + H+ [extracellular] <=> lactate + H+ [cytosol] [Gallus gallus] |
| (updatedInstance) | [_UpdateTracker:9874457] Update Tracker - [SimpleEntity:29708] LACT [cytosol] - v43:[addName] [_UpdateTracker:9891830] Update Tracker - [SimpleEntity:29708] LACT [cytosol] - v52:[addName] |
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No pathways have been reviewed or authored by LACT [cytosol] (29708)