Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person L-Leu [cytosol]

Class:IdSimpleEntity:29588
_displayNameL-Leu [cytosol]
_timestamp2016-10-27 13:08:35
compartment[Compartment:70101] cytosol
crossReference[DatabaseIdentifier:29589] COMPOUND:C00123
modified[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:2537470] Wu, G, 2012-10-26
[InstanceEdit:8943615] D'Eustachio, Peter, 2016-10-27
[InstanceEdit:9616752] Shorser, Solomon, 2018-08-13
[InstanceEdit:9619952] Wu, G, 2018-09-19
nameL-Leu
2-amino-4-methylvaleric acid
L-leucine zwitterion
L-leucine
(2S)-alpha-2-Amino-4-methylvaleric acid
(2S)-alpha-Leucine
referenceEntity[ReferenceMolecule:8943614] L-leucine zwitterion [ChEBI:57427]
stableIdentifier[StableIdentifier:367610] R-ALL-29588.4
(hasComponent)[Complex:9639290] SESN1,2:L-Leu [cytosol] [Homo sapiens]
[Complex:9640244] LARS:L-Leu [cytosol] [Homo sapiens]
(hasMember)[DefinedSet:352048] ligands of SLC6A15 [cytosol]
[DefinedSet:352088] ligands of SLC38A2 [cytosol]
[DefinedSet:352114] ligands of SLC43A1,2 [cytosol]
[DefinedSet:352190] ligands of SLC7A8 [cytosol]
[DefinedSet:352227] ligands of SLC7A5 [cytosol]
[DefinedSet:375459] SLC6A14 ligands [cytosol]
[DefinedSet:375481] neutral amino acids [cytosol]
[DefinedSet:508182] Leu, Ile, Val [cytosol]
(input)[Reaction:379432] SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu [Homo sapiens]
[Reaction:379974] leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate [Homo sapiens]
[Reaction:1113156] leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate [Oryza sativa]
[FailedReaction:5655702] Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu [Homo sapiens]
[FailedReaction:5660890] Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu [Homo sapiens]
[BlackBoxEvent:9639287] SESN1,2 binds L-leucine and dissociates from GATOR2 [Homo sapiens]
(output)[Reaction:379415] SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane [Homo sapiens]
[Reaction:379426] SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine [Homo sapiens]
[Reaction:1120261] indole-3-acetyl-leu+H2O->indole-3-acetate+L-leucine [Oryza sativa]
[Reaction:1121224] Branched-chain amino acid aminotransferase [Oryza sativa]
(updatedInstance)[_UpdateTracker:9874324] Update Tracker - [SimpleEntity:29588] L-Leu [cytosol] - v43:[addName]
[_UpdateTracker:9891032] Update Tracker - [SimpleEntity:29588] L-Leu [cytosol] - v52:[modifyName]
[_UpdateTracker:9895730] Update Tracker - [SimpleEntity:29588] L-Leu [cytosol] - v59:[addName, add_removeReferenceEntity]
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No pathways have been reviewed or authored by L-Leu [cytosol] (29588)