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Details on Person GSH [cytosol]
| Class:Id | SimpleEntity:29450 |
| _displayName | GSH [cytosol] |
| _timestamp | 2021-07-19 18:51:36 |
| compartment | [Compartment:70101] cytosol |
| crossReference | [DatabaseIdentifier:29451] COMPOUND:C00051 |
| modified | [InstanceEdit:113469] Schmidt, EE, 2004-05-17 12:03:06 [InstanceEdit:1641508] Jassal, B, 2011-10-11 [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9618040] Gupta, Parul, 2018-09-03 [InstanceEdit:9619952] Wu, G, 2018-09-19 [InstanceEdit:9737460] D'Eustachio, Peter, 2021-07-19 |
| name | GSH Reduced glutathione glutathione 5-L-Glutamyl-L-cysteinylglycine N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine gamma-L-Glutamyl-L-cysteinyl-glycine glutathionate(1-) |
| referenceEntity | [ReferenceMolecule:9737458] glutathionate(1-) [ChEBI:57925] |
| stableIdentifier | [StableIdentifier:368870] R-ALL-29450.4 |
| (hasComponent) | [Complex:71166] GSTZ1 dimer [cytosol] [Homo sapiens] [Complex:2142683] HPGDS dimer [cytosol] [Homo sapiens] [Complex:9618064] As(III)-PC [cytosol] [Oryza sativa] |
| (input) | [Reaction:71676] GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O [Homo sapiens] [Reaction:111746] glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) [Homo sapiens] [Reaction:159207] 4-hydroxynonenal can form a glutathione conjugate [Homo sapiens] [Reaction:159249] Benzo(a)pyrene-7,8-diol 9,10-epoxide (BPDE) can form a glutathione conjugate [Homo sapiens] [Reaction:176054] GST dimers conjugate GSH with cytosolic substrates [Homo sapiens] [Reaction:198813] GSTO dimers reduce DeHA to AscH- [Homo sapiens] [Reaction:266050] LTA4 is converted to LTC4 by LTC4S [Homo sapiens] [Reaction:1120227] Phospholipid-hydroperoxide glutathione peroxidase [Oryza sativa] [Reaction:1120419] Protein-disulfide reductase (glutathione) [Oryza sativa] [Reaction:1120948] a 5-L-glutamyl-L-amino acid+Cys-Gly->a standard alpha amino acid+glutathione [Oryza sativa] |
| (output) | [Reaction:71682] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Homo sapiens] [Reaction:174394] GSS:Mg2+ dimer synthesizes GSH [Homo sapiens] [Reaction:1120163] glutathione synthetase [Oryza sativa] [Reaction:1120206] Glutathione-disulfide reductase [Oryza sativa] [Reaction:2408514] GSSeSG is reduced to GSSeH and GSH by Gsr [Rattus norvegicus] [Reaction:2408542] GSSeSG is reduced to GSSeH and GSH by GSR [Homo sapiens] [BlackBoxEvent:5333608] GSSebGalNac is reduced and methylated to MeSebGalNac [Homo sapiens] [BlackBoxEvent:5333614] GSSebGalNac is reduced and methylated to MeSebGalNac [Rattus norvegicus] [Reaction:9919982] NS5 is glutathionylated [Homo sapiens] |
| (regulator) | [NegativeRegulation:1260991] Negative regulation by 'GSH [cytosol]' |
| (updatedInstance) | [_UpdateTracker:9891570] Update Tracker - [SimpleEntity:29450] GSH [cytosol] - v52:[modifyName] [_UpdateTracker:9902480] Update Tracker - [SimpleEntity:29450] GSH [cytosol] - v78:[addName, add_removeReferenceEntity] |
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No pathways have been reviewed or authored by GSH [cytosol] (29450)