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Details on Person GTP [cytosol]

Class:IdSimpleEntity:29438
_displayNameGTP [cytosol]
_timestamp2021-07-09 22:34:52
compartment[Compartment:70101] cytosol
crossReference[DatabaseIdentifier:29439] COMPOUND:C00044
modified[InstanceEdit:110413] Schmidt, EE, 2004-02-02 06:03:57
[InstanceEdit:111622] Gopinathrao, G, 2004-03-01 18:40:00
[InstanceEdit:111852] Schmidt, EE, 2004-03-24 06:49:11
[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:5359107] Williams, MG, 2014-04-08
[InstanceEdit:8964250] Varusai, Thawfeek, 2017-02-16
[InstanceEdit:8964452] Varusai, Thawfeek, 2017-02-17
[InstanceEdit:9616752] Shorser, Solomon, 2018-08-13
[InstanceEdit:9736414] D'Eustachio, Peter, 2021-07-09
nameGTP
Guanosine 5'-triphosphate
GTP)(4-)
referenceEntity[ReferenceMolecule:9736415] GTP(4-) [ChEBI:37565]
stableIdentifier[StableIdentifier:367669] R-ALL-29438.4
(hasComponent)[Complex:72503] eIF5B:GTP [cytosol] [Homo sapiens]
[Complex:72531] eIF2:GTP [cytosol] [Homo sapiens]
[Complex:74049] GNAT1-GTP [photoreceptor disc membrane] [Homo sapiens]
[Complex:109783] p21 RAS:GTP [plasma membrane] [Homo sapiens]
[Complex:110415] DRheb-GTP complex [plasma membrane] [Drosophila melanogaster]
[Complex:111855] G-protein alpha (q/11): GTP [plasma membrane] [Homo sapiens]
[Complex:112373] p21 Ras:GTP [plasma membrane] [Rattus norvegicus]
[Complex:114525] G-protein alpha (12):GTP [plasma membrane] [Homo sapiens]
[Complex:114534] G-protein alpha (q/11): GTP [plasma membrane] [Homo sapiens]
[Complex:114539] VAV1 Rho/Rac effectors:GTP [cytosol] [Homo sapiens]
List all 321 refering instances
(hasMember)[DefinedSet:170037] Purine nucleotide [cytosol]
[DefinedSet:482625] (d)NTP [cytosol]
[DefinedSet:9974597] SLC22A7 end. metabolite cargo [cytosol]
(input)[Reaction:70241] PCK1 phosphorylates OA to yield PEP [Homo sapiens]
[Reaction:72663] De novo formation of eIF2:GTP [Homo sapiens]
[Reaction:72722] eIF2 activation [Homo sapiens]
[Reaction:74885] GUCYs converts GTP to cGMP [Homo sapiens]
[Reaction:109807] GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS [Homo sapiens]
[Reaction:109817] GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS [Homo sapiens]
[Reaction:109825] (Controversial - not included in public release.) SOS mediated nucleotide exchange of RAS (IRS, Crk) [Homo sapiens]
[Reaction:111519] inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate [Mus musculus]
[Reaction:111524] IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] [Homo sapiens]
[Reaction:111525] inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate [Mus musculus]
List all 332 refering instances
(output)[Reaction:167415] G-protein alpha subunit is inactivated [Homo sapiens]
[Reaction:428520] Inactivation of Rac1 [Drosophila melanogaster]
[Reaction:983422] Disassembly of COPII coated vesicle [Homo sapiens]
[Reaction:9029152] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Y-Crkl:p-Y-Shc1:Grb2-1:Sos1,p-Y-Vav1 mediates exchange of GDP for GTP bound to Ras [Mus musculus]
[Reaction:9611415] dephosphorylation of Rac1:GTP [Oryza sativa]
[Reaction:9639286] RRAGC,D exchanges GTP for GDP [Homo sapiens]
[BlackBoxEvent:9958874] 26S proteasome degrades ubiquitinated RAC1, CDC42 [Homo sapiens]
[BlackBoxEvent:9984065] 26S proteasome degrades ubiquitinated Rac1, Cdc42 [Mus musculus]
(regulator)[Requirement:72779] Requirement by 'GTP [cytosol]'
[Requirement:1112810] Requirement by 'GTP [cytosol]'
[Requirement:1592858] Requirement by 'GTP [cytosol]'
[PositiveRegulation:9909286] Positive regulation by 'GTP [cytosol]'
(replacementInstances)[_Deleted:8979624] Deletion of instances: 8964431, 113572
(updatedInstance)[_UpdateTracker:9902648] Update Tracker - [SimpleEntity:29438] GTP [cytosol] - v78:[addName, add_removeReferenceEntity]
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No pathways have been reviewed or authored by GTP [cytosol] (29438)
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