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Details on Person Phosphorylated Stat5 Dimer Translocates to the Nucleus

Class:Id	BlackBoxEvent:2730596
_displayName	Phosphorylated Stat5 Dimer Translocates to the Nucleus
_doRelease	TRUE
_timestamp	2013-10-26 10:18:19
authored	[InstanceEdit:2730589] May, B, 2012-12-03
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:2730594] May, B, 2012-12-04
edited	[InstanceEdit:2730589] May, B, 2012-12-03
input	[Complex:2730591] p-Stat5 dimer [cytosol] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:2730552] Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner [LiteratureReference:2730611] Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors [LiteratureReference:507814] Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells
modified	[InstanceEdit:2730625] May, B, 2012-12-04 [InstanceEdit:2752153] May, B, 2012-12-08 [InstanceEdit:3110011] May, B, 2013-02-10 [InstanceEdit:3631763] May, B, 2013-05-25 [InstanceEdit:4420241] May, B, 2013-08-31 [InstanceEdit:4789069] May, B, 2013-10-26 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylated Stat5 Dimer Translocates to the Nucleus
output	[Complex:2730588] p-Stat5 dimer [nucleoplasm] [Mus musculus]
precedingEvent	[Reaction:2730593] Phosphorylated Stat5 dimerizes [Mus musculus] [Reaction:2671832] Phosphorylated Stat5 Dissociates from Leptin Receptor [Mus musculus]
releaseDate	2013-09-18
reviewed	[InstanceEdit:4420239] Scherer, Thomas, 2013-08-31 [InstanceEdit:4789050] Gonzalez-Perez, Ruben Rene, 2013-10-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:4545298] R-MMU-2730596.2
summation	[Summation:2730608] Homodimers and heterodimers of phosphoryated Stat5a and Stat...
(inferredFrom)	[BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus [Homo sapiens]
(replacementInstances)	[_Deleted:9032439] Deletion of instance: 2586551 [_Deleted:9032440] Deletion of instance: 5334727
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No pathways have been reviewed or authored by Phosphorylated Stat5 Dimer Translocates to the Nucleus (2730596)