Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q7XM21 F3H-1
| Class:Id | ReferenceGeneProduct:2672430 |
|---|---|
| _chainChangeLog | chain:1-377 for 2672430 added on Fri Nov 03 2023 |
| _displayName | UniProt:Q7XM21 F3H-1 |
| _timestamp | 2025-02-21 18:46:53 |
| chain | chain:1-377 |
| checksum | E5704DAB62538B1E |
| comment | FUNCTION Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. Converts (2S)-eriodictyol to (+)-taxifolin and (2S)-naringenin to (+)-(2R/3R)-dihydrokaempferol in vitro.CATALYTIC ACTIVITY a (2S)-flavan-4-one + 2-oxoglutarate + O2 = a (2R,3R)-dihydroflavonol + succinate + CO2COFACTOR Binds 1 Fe(2+) ion per subunit.COFACTOR Secondary metabolite biosynthesis; flavonoid biosynthesis.TISSUE SPECIFICITY Expressed at low levels in roots, leaves, stems and seeds.SIMILARITY Belongs to the iron/ascorbate-dependent oxidoreductase family. |
| created | [InstanceEdit:2672435] D'Eustachio, P, 2012-11-27 |
| description | recommendedName: fullName evidence="6"Flavanone 3-dioxygenase 1 ecNumber evidence="4"1.14.11.9 alternativeName: fullName evidence="6"Flavanone 3-beta-hydroxylase 1 alternativeName: fullName evidence="5"Flavanone 3-hydroxylase 1 shortName evidence="5"OsF3H-1 |
| geneName | F3H-1 Os04g0662600 LOC_Os04g56700 OSJNBa0084K01.10 |
| identifier | Q7XM21 |
| isSequenceChanged | FALSE |
| keyword | Dioxygenase Flavonoid biosynthesis Iron Metal-binding Oxidoreductase Reference proteome Vitamin C |
| modified | [InstanceEdit:2672444] D'Eustachio, P, 2012-11-27 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | F3H-1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | FL3H1_ORYSJ A0A0P0WFY8 C7J0Y2 |
| sequenceLength | 377 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:2672431] Flavanone-3-hydroxylase, putative (LOC_Os04g56700.1) [cytosol] [Oryza sativa subsp. japonica] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q7XM21 F3H-1 (2672430)
