Query author contributions in Reactome
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Details on Person As inferred from mouse, SOCS3 binds LEPR at phosphotyrosine-...
| Class:Id | Summation:2672308 |
|---|---|
| _displayName | As inferred from mouse, SOCS3 binds LEPR at phosphotyrosine-... |
| _timestamp | 2012-12-27 20:13:38 |
| created | [InstanceEdit:2672306] May, B, 2012-11-27 |
| modified | [InstanceEdit:2883082] May, B, 2012-12-27 |
| text | As inferred from mouse, SOCS3 binds LEPR at phosphotyrosine-986 and phosphotyrosine-1079. SOCS3 competes with SHP2 (PTPN11) for phosphotyrosine-986 and with STAT5 for phosphotyrosine-1079. SOCS3 expression is upregulated by leptin and SOCS3 downregulates prolonged leptin signaling, providing a feedback loop to limit leptin's action. |
| (summation) | [Reaction:2672302] Phosphorylated LEPR Binds SOCS3 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by As inferred from mouse, SOCS3 binds LEPR at phosphotyrosine-... (2672308)
