Query author contributions in Reactome
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Details on Person FA protein FANCI has been identified as an ATM/ATR kinase su...
| Class:Id | Summation:265955 |
|---|---|
| _displayName | FA protein FANCI has been identified as an ATM/ATR kinase su... |
| _timestamp | 2008-07-25 17:02:42 |
| created | [InstanceEdit:265962] Saxena, A, 2008-04-21 13:32:36 |
| modified | [InstanceEdit:374078] Saxena, A, 2008-07-25 17:02:19 |
| text | FA protein FANCI has been identified as an ATM/ATR kinase substrate required for cellular resistance to mitomycin C. FANCI shares sequence similarity with FANCD2, likely evolving from a common ancestral gene. The FANCI protein associates with FANCD2 and, together, as the FANCI FANCD2 (ID) complex, localize to chromatin in response to DNA damage. FANCD2-FANCI interdependent monoubiquitination is important for the maintenance of ubiquitin on the other, indicating the existence of a dual ubiquitin-locking mechanism required for ID complex function and hence DNA repair. |
| (summation) | [Reaction:265973] Monoubiquitination of FANCI [Gallus gallus] |
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No pathways have been reviewed or authored by FA protein FANCI has been identified as an ATM/ATR kinase su... (265955)
