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Details on Person Phosphorylation of RPA2 by CDC2 kinase

Class:Id	Reaction:265936
_displayName	Phosphorylation of RPA2 by CDC2 kinase
_doRelease	TRUE
_timestamp	2011-11-23 11:14:06
authored	[InstanceEdit:209713] Saxena, A, 2008-01-04 18:30:50
catalystActivity	[CatalystActivity:265937] protein serine/threonine kinase activity of CDC2 kinase, Cell division control protein 2 homolog [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:265962] Saxena, A, 2008-04-21 13:32:36
edited	[InstanceEdit:418967] D'Eustachio, P, 2009-04-27 17:09:41
input	[EntityWithAccessionedSequence:265807] RCF4 [nucleoplasm] [Gallus gallus] [SimpleEntity:29358] ATP [nucleoplasm]
literatureReference	[LiteratureReference:265865] DNA unwinding by replication protein A is a property of the 70 kDa subunit and is facilitated by phosphorylation of the 32 kDa subunit [LiteratureReference:265868] Phosphorylation of replication protein A by S-phase checkpoint kinases [LiteratureReference:265878] Phosphorylation of replication protein A middle subunit (RPA32) leads to a disassembly of the RPA heterotrimer [LiteratureReference:391632] Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair
modified	[InstanceEdit:391641] Saxena, A, 2009-02-23 15:55:32 [InstanceEdit:418476] D'Eustachio, P, 2009-04-22 20:40:00 [InstanceEdit:418618] D'Eustachio, P, 2009-04-24 15:53:07 [InstanceEdit:418966] D'Eustachio, P, 2009-04-27 17:13:45 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylation of RPA2 by CDC2 kinase
output	[EntityWithAccessionedSequence:265827] phospho-RCF4 [nucleoplasm] [Gallus gallus] [SimpleEntity:113582] ADP [nucleoplasm]
precedingEvent	[Reaction:265887] Binding of RPA heterotrimer to 3' double stranded DNA break [Gallus gallus] [Reaction:217209] Generation of a DNA double strand break [Gallus gallus]
releaseDate	2009-06-01
reviewed	[InstanceEdit:418616] Borowiec, JA, 2009-04-23 20:19:22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:2016547] R-GGA-265936.2
summation	[Summation:265957] Replication protein A (RPA) is a heterotrimeric single stran...
(hasEvent)	[Pathway:265976] Homologous DNA pairing and strand exchange [Gallus gallus] [Pathway:351451] Homologous recombination repair of replication-dependent double-strand breaks [Gallus gallus]
(updatedInstance)	[_UpdateTracker:9782493] Update Tracker - [Reaction:265936] Phosphorylation of RPA2 by CDC2 kinase - v59:[modifyText]
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No pathways have been reviewed or authored by Phosphorylation of RPA2 by CDC2 kinase (265936)