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Details on Person KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

Class:IdComplex:265734
_displayNameKCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]
_timestamp2015-08-06 18:29:22
compartment[Compartment:876] plasma membrane
created[InstanceEdit:265678] May, B, 2008-04-20 07:49:26
hasComponent
literatureReference[LiteratureReference:1296246] Inwardly rectifying potassium channels: their structure, function, and physiological roles
modified[InstanceEdit:448769] May, B, 2009-11-26
[InstanceEdit:5683200] Jassal, Bijay, 2015-03-12
[InstanceEdit:6790055] May, Bruce, 2015-08-06
nameKCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer
Inward Rectifying Potassium Channel (open)
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:398633] R-HSA-265734.2
(hasComponent)[Complex:9650859] ABCC8:Meglitinides [plasma membrane] [Homo sapiens]
[Complex:9652593] ABCC8:SU drugs [plasma membrane] [Homo sapiens]
(input)[Reaction:265682] KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel [Homo sapiens]
[Reaction:9650858] Meglitinides bind ABCC8 [Homo sapiens]
[Reaction:9652580] SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:5683172] loss_of_function of KCNJ11 tetramer:ABCC8 mutants [plasma membrane]
(physicalEntity)[CatalystActivity:264517] ATP binding activity of KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]
[CatalystActivity:5683169] ATP-activated inward rectifier potassium channel activity of KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]
(updatedInstance)[_UpdateTracker:9868537] Update Tracker - [Complex:265734] KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] - v31:[add_removeHasComponent]
[_UpdateTracker:9892503] Update Tracker - [Complex:265734] KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] - v53:[addName]
[_UpdateTracker:9893010] Update Tracker - [Complex:265734] KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] - v54:[addLiteratureReference, add_removeHasComponent, modifyName]
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No pathways have been reviewed or authored by KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] (265734)
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