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Details on Person Prostaglandin E synthase isomerizes PGH2 to PGE2

Class:IdReaction:265295
_displayNameProstaglandin E synthase isomerizes PGH2 to PGE2
_doReleaseTRUE
_timestamp2024-07-12 21:31:48
authored[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
catalystActivity[CatalystActivity:265290] prostaglandin-E synthase activity of PTGES2(88-377), PTGES3 [cytosol]
catalystActivityReference[CatalystActivityReference:9915626] prostaglandin-E synthase activity of PTGES2(88-377), PTGES3 [cytosol] Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis
compartment[Compartment:70101] cytosol
created[InstanceEdit:265270] Jassal, B, 2008-04-17 12:12:14
crossReference[DatabaseIdentifier:9915666] RHEA:12894
input[SimpleEntity:265283] PGH2 [cytosol]
literatureReference[LiteratureReference:265291] Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis
[LiteratureReference:8864245] Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2
modified[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
[InstanceEdit:380824] Jassal, Bijay, 2008-11-17
[InstanceEdit:383321] Jassal, B, 2008-11-25 10:01:15
[InstanceEdit:387041] D'Eustachio, P, 2008-11-29 18:16:22
[InstanceEdit:561301] D'Eustachio, P, 2010-04-02
[InstanceEdit:2303722] D'Eustachio, P, 2012-06-04
[InstanceEdit:2460023] Matthews, L, 2012-08-29
[InstanceEdit:2569041] D'Eustachio, P, 2012-11-10
[InstanceEdit:8864249] Jupe, Steve, 2016-03-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9915663] D'Eustachio, Peter, 2024-07-12
nameProstaglandin E synthase isomerizes PGH2 to PGE2
prostaglandin H2 => prostaglandin E2
output[SimpleEntity:265287] PGE2 [cytosol]
precedingEvent
releaseDate2008-12-17
reviewed[InstanceEdit:2569042] Rush, MG, 2012-11-10
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:387722] R-HSA-265295.4
summation[Summation:265272] Prostaglandin E2 (PGE2) is the most abundant prostanoid in t...
(hasEvent)[Pathway:2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9783149] Update Tracker - [Reaction:265295] Prostaglandin E synthase isomerizes PGH2 to PGE2 - v57:[addLiteratureReference, modifyText]
[_UpdateTracker:9788653] Update Tracker - [Reaction:265295] Prostaglandin E synthase isomerizes PGH2 to PGE2 - v41:[modifyText]
[_UpdateTracker:9919447] Update Tracker - [Reaction:265295] Prostaglandin E synthase isomerizes PGH2 to PGE2 - v90:[modifyText]
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