Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person Translocon:TRAP [endoplasmic reticulum membrane]
Class:Id Complex:264969
_displayName Translocon:TRAP [endoplasmic reticulum membrane]
_timestamp 2026-04-11 02:17:54
compartment [Compartment:12045] endoplasmic reticulum membrane
created [InstanceEdit:265053] May, B, 2008-04-15 03:12:38
goCellularComponent [GO_CellularComponent:17952] Sec61 translocon complex
hasComponent
inferredFrom
literatureReference [LiteratureReference:444584] Endoplasmic reticulum-bound ribosomes reside in stable association with the translocon following termination of protein synthesis [LiteratureReference:9986832] Structural analysis of the dynamic ribosome-translocon complex
modified [InstanceEdit:349824] May, B, 2008-05-13 12:22:36 [InstanceEdit:444586] May, B, 2009-10-24 [InstanceEdit:981572] May, B, 2010-10-25 [InstanceEdit:1799328] D'Eustachio, P, 2011-10-23 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9986856] May, Bruce, 2026-04-06 [InstanceEdit:9987264] May, Bruce, 2026-04-11 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
name Translocon:TRAP
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:387850] R-HSA-264969.19
(hasComponent) [Complex:265047] Preproinsulin-Translocon Complex [endoplasmic reticulum membrane] [Homo sapiens] [Complex:934665] Preprolactin:Translocon Complex [endoplasmic reticulum membrane] [Homo sapiens] [Complex:1799322] polypeptide+signal:Translocon [endoplasmic reticulum membrane] [Homo sapiens] [Complex:1799324] cleaved polypeptide:Translocon [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9986696] SEC61 translocon:TRAP:nascent membrane polypeptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9986700] Translocon:TRAP:MPT:nascent multipass ER membrane polypeptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9987021] SEC61 translocon:TRAP:OST:nascent membrane polypeptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9988077] SEC61 translocon:TRAP:nascent ER membrane polypeptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9988085] Translocon:TRAP:nascent ER-targeted polypeptide with signal peptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9988086] SEC61 translocon:TRAP:nascent soluble ER polypeptide minus signal peptide:80S ribosome:mRNA [Homo sapiens]
(input) [Reaction:934660] Translocation of Preprolactin to the Endoplasmic Reticulum [Homo sapiens] [Reaction:1799326] Signal-containing nascent peptide translocates to endoplasmic reticulum [Homo sapiens] [Reaction:9986704] SRP:SRP receptor transfers nascent membrane polypeptide to SEC61 translocon:TRAP complex [Homo sapiens] [Reaction:9988089] SRP:GTP:SRP receptor:GTP transfers nascent polypeptide containing signal peptide or signal anchor to SEC61 translocon:TRAP complex [Homo sapiens]
(output) [Reaction:934647] Cleavage of the Signal Peptide of Preprolactin [Homo sapiens] [BlackBoxEvent:9986727] SEC61 translocon:TRAP inserts protein into endoplasmic reticulum membrane [Homo sapiens] [BlackBoxEvent:9986731] Multipass translocon (MPT) inserts protein into endoplasmic reticulum membrane [Homo sapiens] [BlackBoxEvent:9987037] SEC61 translocon:TRAP:OST inserts protein into endoplasmic reticulum membrane [Homo sapiens] [BlackBoxEvent:9988079] SEC61 translocon:TRAP complex releases ER-targeted membrane protein into ER membrane [Homo sapiens] [BlackBoxEvent:9988097] SEC61 translocon:TRAP complex translocates soluble ER-targeted protein into the ER lumen [Homo sapiens]
(updatedInstance) [_UpdateTracker:9868484] Update Tracker - [Complex:264969] Translocon:TRAP [endoplasmic reticulum membrane] - v31:[addLiteratureReference, add_removeHasComponent, modifyName] [_UpdateTracker:9869824] Update Tracker - [Complex:264969] Translocon:TRAP [endoplasmic reticulum membrane] - v35:[addHasComponent] [_UpdateTracker:9871118] Update Tracker - [Complex:264969] Translocon:TRAP [endoplasmic reticulum membrane] - v39:[modifyName] [_UpdateTracker:9888953] Update Tracker - [Complex:264969] Translocon:TRAP [endoplasmic reticulum membrane] - v48:[updateContainedComponent] [_UpdateTracker:9901867] Update Tracker - [Complex:264969] Translocon:TRAP [endoplasmic reticulum membrane] - v75:[updateContainedComponent]
[Change default viewing format]
List...
Protein identifiers
No pathways have been reviewed or authored by Translocon:TRAP [endoplasmic reticulum membrane] (264969)