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Details on Person cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)

Class:Id	Reaction:264695
_displayName	cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)
_doRelease	TRUE
_timestamp	2022-02-15 19:56:47
authored	[InstanceEdit:349660] D'Eustachio, P, 2008-05-12 17:46:52
catalystActivity	[CatalystActivity:264680] phosphatidylcholine-sterol O-acyltransferase activity of LCAT [extracellular region]
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:264681] D'Eustachio, P, 2008-04-05 20:14:13
edited	[InstanceEdit:353690] D'Eustachio, P, 2008-06-13 14:03:50
input	[SimpleEntity:171149] CHOL [extracellular region] [SimpleEntity:382539] PC [extracellular region]
literatureReference	[LiteratureReference:264675] A protein cofactor of lecithin:cholesterol acyltransferase [LiteratureReference:264676] Lecithin: cholesterol acyltransferase: effects of substrate composition upon enzyme activity [LiteratureReference:264686] Structural and functional properties of two mutants of lecithin-cholesterol acyltransferase (T123I and N228K)
modified	[InstanceEdit:266316] D'Eustachio, P, 2008-05-05 14:22:58 [InstanceEdit:266359] Gopinathrao, G, 2008-05-06 14:37:06 [InstanceEdit:349666] D'Eustachio, P, 2008-05-12 17:50:01 [InstanceEdit:353692] D'Eustachio, P, 2008-06-13 14:06:33 [InstanceEdit:8964195] D'Eustachio, Peter, 2017-02-15 [InstanceEdit:8964415] D'Eustachio, Peter, 2017-02-16 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9765529] D'Eustachio, Peter, 2022-02-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)
output	[SimpleEntity:171076] CHEST [extracellular region] [SimpleEntity:194236] 1-acyl LPC [extracellular region]
regulatedBy	[PositiveRegulation:264701] Positive regulation by 'APOA1(25-266) [extracellular region]'
releaseDate	2008-06-30
reviewed	[InstanceEdit:353689] Jassal, Bijay, 2008-06-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359135] R-HSA-264695.5
summation	[Summation:264691] LCAT activated by apoA-I catalyzes the reaction of cholester...
(hasEvent)	[Pathway:8964058] HDL remodeling [Homo sapiens]
(precedingEvent)	[Reaction:264679] Serum albumin binds 2-lysophosphatidylcholine [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775072] Update Tracker - [Reaction:264695] cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) - v80:[add_removeInput]
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No pathways have been reviewed or authored by cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (264695)