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Details on Person HSPA8 [cytosol]

Class:IdEntityWithAccessionedSequence:264476
_displayNameHSPA8 [cytosol]
_timestamp2013-05-03 18:44:28
compartment[Compartment:70101] cytosol
created[InstanceEdit:264474] Gillespie, ME, 2008-03-31 20:31:49
endCoordinate646
modified[InstanceEdit:351199] Gillespie, ME, 2008-05-21 20:31:41
[InstanceEdit:449684] May, B, 2009-12-04
[InstanceEdit:3132750] Wu, G, 2013-02-13
[InstanceEdit:3322333] Wu, G, 2013-05-03
[InstanceEdit:3322334] Wu, G, 2013-05-03
[InstanceEdit:3448660] Wu, G, 2013-05-16
nameHSPA8
Heat shock cognate 71 kDa protein
HSP7C_HUMAN
HSC70
referenceEntity[ReferenceGeneProduct:56692] UniProt:P11142 HSPA8 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:377988] R-HSA-264476.1
startCoordinate2
(activeUnit)[CatalystActivity:8868656] ATP hydrolysis activity of PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane]
[PositiveRegulation:9837540] Positive regulation by 'HSPA8 [cytosol]'
(hasComponent)[Complex:351175] HSC70:Auxillin Complex [cytosol] [Homo sapiens]
[Complex:445018] CHL1:HSP7C [plasma membrane] [Homo sapiens]
[Complex:450623] AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] [Homo sapiens]
[Complex:5251932] HSPA8:ADP [cytosol] [Homo sapiens]
[Complex:5251937] HSPA8:ATP [cytosol] [Homo sapiens]
[Complex:9613350] PLINs:HSPA8 [lipid droplet] [Homo sapiens]
[Complex:9613533] p-PLINs:HSPA8 [lipid droplet] [Homo sapiens]
[Complex:9615717] HSPA8 bound autophagic substrates [cytosol] [Homo sapiens]
[Complex:9620192] p-PLINs:HSPA8 [cytosol] [Homo sapiens]
[Complex:9626246] HSPA8:LAMP2a multimers [lysosomal membrane] [Homo sapiens]
List all 11 refering instances
(hasMember)[CandidateSet:3299408] HSP70 proteins [cytosol] [Homo sapiens]
[DefinedSet:6797275] HSPA8, ALOX15 [cytosol] [Homo sapiens]
(input)[Reaction:445087] CHL1 interacts with HSP7C [Homo sapiens]
[Reaction:450551] AUF1 binds translation and heat shock proteins [Homo sapiens]
[Reaction:9613352] PLINs bind HSPA8 [Homo sapiens]
[Reaction:9615721] HSPA8 binds substrate [Homo sapiens]
[Reaction:9626253] HSPA8 binds LAMP2a multimers [Homo sapiens]
[Reaction:9922140] NS3 binds HSPA8 [Homo sapiens]
(output)[Reaction:9622840] HSPA8 dissociates from LAMP2A-bound substrate [Homo sapiens]
[Reaction:9626235] HSPA8 dissociates from LAMP2a [Homo sapiens]
(regulator)[PositiveRegulation:9837540] Positive regulation by 'HSPA8 [cytosol]'
[Requirement:9925429] Requirement by 'HSPA8 [cytosol]'
(updatedInstance)[_UpdateTracker:9869029] Update Tracker - [EntityWithAccessionedSequence:264476] HSPA8 [cytosol] - v32:[addName]
[_UpdateTracker:9878436] Update Tracker - [EntityWithAccessionedSequence:264476] HSPA8 [cytosol] - v44:[addEndCoordinate, addStartCoordinate]
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No pathways have been reviewed or authored by HSPA8 [cytosol] (264476)
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