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Details on Person Proteasome mediated degradation of COP1

Class:IdBlackBoxEvent:264458
_displayNameProteasome mediated degradation of COP1
_doReleaseTRUE
_timestamp2016-11-10 00:56:44
authored[InstanceEdit:353601] Matthews, L, 2008-06-12 21:09:06
catalystActivity[CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:264456] Matthews, L, 2008-03-31 12:27:17
edited[InstanceEdit:446058] Matthews, L, 2009-11-09
input[Complex:349433] ubiquitinated phospho-COP1(ser-387) [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:349437] ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage
modified[InstanceEdit:349466] Matthews, L, 2008-05-07 22:49:21
[InstanceEdit:352043] Matthews, L, 2008-05-29 21:34:10
[InstanceEdit:352487] Matthews, L, 2008-06-03 01:05:59
[InstanceEdit:354039] Matthews, L, 2008-06-14 07:27:44
[InstanceEdit:446709] Matthews, L, 2009-11-17
[InstanceEdit:446713] Matthews, L, 2009-11-17
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameProteasome mediated degradation of COP1
output[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
precedingEvent
releaseDate2009-12-15
reviewed[InstanceEdit:446711] Dixit, VM, 2009-11-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105785] R-HSA-264458.3
summation[Summation:349468] Autoubiquitinated COP1 is degraded by the proteasome. The nu...
(hasEvent)[Pathway:349425] Autodegradation of the E3 ubiquitin ligase COP1 [Homo sapiens]
(precedingEvent)[NegativePrecedingEvent:9749040] Abundant Molecules: Proteasome mediated degradation of COP1
[NegativePrecedingEvent:9749042] Abundant Molecules: Proteasome mediated degradation of COP1
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