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Details on Person Translocation of COP1 from the nucleus to the cytoplasm

Class:Id	Reaction:264418
_displayName	Translocation of COP1 from the nucleus to the cytoplasm
_doRelease	TRUE
_timestamp	2017-04-24 17:04:48
authored	[InstanceEdit:353601] Matthews, L, 2008-06-12 21:09:06
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:264440] Matthews, L, 2008-03-31 11:49:44
edited	[InstanceEdit:446058] Matthews, L, 2009-11-09
input	[EntityWithAccessionedSequence:349450] p-S387-RFWD2 [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:349437] ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage
modified	[InstanceEdit:349466] Matthews, L, 2008-05-07 22:49:21 [InstanceEdit:352043] Matthews, L, 2008-05-29 21:34:10 [InstanceEdit:352490] Matthews, L, 2008-06-03 01:07:17 [InstanceEdit:354040] Matthews, L, 2008-06-14 07:28:08 [InstanceEdit:446709] Matthews, L, 2009-11-17 [InstanceEdit:446713] Matthews, L, 2009-11-17 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8986252] Rothfels, Karen, 2017-04-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of COP1 from the nucleus to the cytoplasm
output	[EntityWithAccessionedSequence:349439] p-S387-RFWD2 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:349444] Phosphorylation of COP1 at Ser-387 by ATM [Homo sapiens] [Reaction:5693540] MRN activates ATM [Homo sapiens] [Reaction:264435] Dissociation of the COP1-p53 complex [Homo sapiens] [Reaction:349444] Phosphorylation of COP1 at Ser-387 by ATM [Homo sapiens]
releaseDate	2009-12-15
reviewed	[InstanceEdit:446711] Dixit, VM, 2009-11-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105344] R-HSA-264418.4
summation	[Summation:349476] Ionizing radiation results in an ATM-dependent movement of C...
(hasEvent)	[Pathway:349425] Autodegradation of the E3 ubiquitin ligase COP1 [Homo sapiens]
(inferredFrom)	[Reaction:1113052] Translocation of COP1 from the nucleus to the cytoplasm [Oryza sativa]
(orthologousEvent)	[Reaction:1113052] Translocation of COP1 from the nucleus to the cytoplasm [Oryza sativa]
(precedingEvent)	[Reaction:264444] Autoubiquitination of phospho-COP1(Ser-387 ) [Homo sapiens]
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No pathways have been reviewed or authored by Translocation of COP1 from the nucleus to the cytoplasm (264418)