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Details on Person 'de novo' NAD+ biosynthetic process from L-tryptophan

Class:IdGO_BiologicalProcess:262876
_displayName'de novo' NAD+ biosynthetic process from L-tryptophan
_timestamp2025-08-15 22:48:43
accession0034354
created[InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20
definitionThe chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD+), beginning with the catabolism of L-tryptophan into the precursor quinolinate. NAD+ is a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions.
modified[InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39
[InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04
[InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44
[InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57
[InstanceEdit:422569] Kanapin, EE
[InstanceEdit:436347] Kanapin, EE
[InstanceEdit:447572] Kanapin, EE
[InstanceEdit:526073] Kanapin, AA
[InstanceEdit:528085] Kanapin, AA
[InstanceEdit:615500] Kanapin, AA
[InstanceEdit:797782] Kanapin, AA
[InstanceEdit:937668] Yung, CK
[InstanceEdit:1042299] Yung, CK
[InstanceEdit:1220942] Yung, CK
[InstanceEdit:1301023] Yung, CK
[InstanceEdit:1552540] Yung, CK
[InstanceEdit:1996004] Yung, CK
[InstanceEdit:2132408] Weiser, JD
[InstanceEdit:2133145] Weiser, JD
[InstanceEdit:2266147] Weiser, JD
[InstanceEdit:2454362] Weiser, JD
[InstanceEdit:2455542] Weiser, JD
[InstanceEdit:2587907] Weiser, JD
[InstanceEdit:3132285] Weiser, JD
[InstanceEdit:3445953] Weiser, JD
[InstanceEdit:4341211] Weiser, JD
[InstanceEdit:5083267] Weiser, JD
[InstanceEdit:5263134] Weiser, JD
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
name'de novo' NAD+ biosynthetic process from L-tryptophan
referenceDatabase[ReferenceDatabase:1] GO
(goBiologicalProcess)[Reaction:197187] ACS transforms to QUIN non-enzymatically [Homo sapiens]
[Reaction:197235] NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD [Homo sapiens]
[Reaction:197268] QPRT transfers PRIB to QUIN to form NAMN [Homo sapiens]
[Reaction:197271] NADSYN1 hexamer amidates NAAD to NAD+ [Homo sapiens]
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