Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person negative regulation of type I interferon production

Class:IdGO_BiologicalProcess:261603
_displayNamenegative regulation of type I interferon production
_timestamp2014-02-11 03:00:04
accession0032480
created[InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20
definitionAny process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
modified[InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39
[InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04
[InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44
[InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57
[InstanceEdit:422569] Kanapin, EE
[InstanceEdit:436347] Kanapin, EE
[InstanceEdit:447572] Kanapin, EE
[InstanceEdit:526073] Kanapin, AA
[InstanceEdit:528085] Kanapin, AA
[InstanceEdit:615500] Kanapin, AA
[InstanceEdit:797782] Kanapin, AA
[InstanceEdit:937668] Yung, CK
[InstanceEdit:1042299] Yung, CK
[InstanceEdit:1220942] Yung, CK
[InstanceEdit:1301023] Yung, CK
[InstanceEdit:1552540] Yung, CK
[InstanceEdit:1996004] Yung, CK
[InstanceEdit:2132408] Weiser, JD
[InstanceEdit:2133145] Weiser, JD
[InstanceEdit:2266147] Weiser, JD
[InstanceEdit:2454362] Weiser, JD
[InstanceEdit:2455542] Weiser, JD
[InstanceEdit:2587907] Weiser, JD
[InstanceEdit:3132285] Weiser, JD
[InstanceEdit:3445953] Weiser, JD
[InstanceEdit:4341211] Weiser, JD
[InstanceEdit:5083267] Weiser, JD
[InstanceEdit:5263134] Weiser, JD
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
namenegative regulation of type I interferon production
referenceDatabase[ReferenceDatabase:1] GO
(goBiologicalProcess)[Pathway:936440] Negative regulators of DDX58/IFIH1 signaling [Homo sapiens]
[Pathway:9711037] Microbial regulators of DDX58/IFIH1 signaling [Homo sapiens]
[Reaction:9724201] PPM1A, PPM1B dephosphorylate TBK1 or IKBKE [Homo sapiens]
[Reaction:9724203] SOCS3 polyubiquitinates TBK1 [Homo sapiens]
[NegativeRegulation:9685157] Negative regulation by 'M [Golgi membrane]'
[NegativeRegulation:9685180] Negative regulation by 'N [cytosol]'
[NegativeRegulation:9717908] Negative regulation by 'PPP1CA, PPP1CC:MeV P/V [cytosol]'
[Change default viewing format]
No pathways have been reviewed or authored by negative regulation of type I interferon production (261603)