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Details on Person Lep:Lepr:p-Jak2 [plasma membrane]

Class:Id	Complex:2586535
_displayName	Lep:Lepr:p-Jak2 [plasma membrane]
_timestamp	2013-09-05 12:00:36
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2586546] May, B, 2012-11-15
hasComponent	[EntityWithAccessionedSequence:2586529] Leptin [extracellular region] [Mus musculus] [EntityWithAccessionedSequence:2586529] Leptin [extracellular region] [Mus musculus] [Complex:2586525] Lepr:p-Jak2 [plasma membrane] [Mus musculus] [Complex:2586544] Lepr dimer [plasma membrane] [Mus musculus] [EntityWithAccessionedSequence:2586522] Lepr (long isoform) [plasma membrane] [Mus musculus] [EntityWithAccessionedSequence:2586522] Lepr (long isoform) [plasma membrane] [Mus musculus] [EntityWithAccessionedSequence:2586515] p-12Y-Jak2 [cytosol] [Mus musculus] [EntityWithAccessionedSequence:2586515] p-12Y-Jak2 [cytosol] [Mus musculus]
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
isChimeric	FALSE
literatureReference	[LiteratureReference:873836] Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity
modified	[InstanceEdit:2672318] May, B, 2012-11-27
name	Lep:Lepr:p-Jak2
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:4545480] R-MMU-2586535.1
(input)	[Reaction:2586557] Jak2 Phosphorylates Lepr [Mus musculus]
(output)	[Reaction:2586548] Jak2 Autophosphorylates in Response to Leptin [Mus musculus]
(physicalEntity)	[CatalystActivity:2586556] protein tyrosine kinase activity of Lep:Lepr:p-Jak2 [plasma membrane]
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No pathways have been reviewed or authored by Lep:Lepr:p-Jak2 [plasma membrane] (2586535)