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Details on Person GRK1,4,7 phosphorylate MII to p-MII
Class:Id Reaction:2581474 _displayName GRK1,4,7 phosphorylate MII to p-MII _doRelease TRUE _timestamp 2015-07-17 13:03:47 authored [InstanceEdit:2581471] Jassal, Bijay, 2012-11-13 catalystActivity [CatalystActivity:2581483] rhodopsin kinase activity of GRK1,4,7 [photoreceptor disc membrane] compartment [Compartment:70101] cytosol [Compartment:2514888] photoreceptor disc membrane created [InstanceEdit:2581471] Jassal, Bijay, 2012-11-13 edited [InstanceEdit:2581471] Jassal, Bijay, 2012-11-13 input [EntityWithAccessionedSequence:5205901] at-retinyl-RHO [photoreceptor disc membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] isChimeric FALSE literatureReference [LiteratureReference:3223220] Characterization and chromosomal localization of the gene for human rhodopsin kinase [LiteratureReference:3222200] Lessons from photoreceptors: turning off G-protein signaling in living cells [LiteratureReference:3222186] Speed, sensitivity, and stability of the light response in rod and cone photoreceptors: facts and models [LiteratureReference:74644] The sequence of human retinal S-antigen reveals similarities with alpha-transducin. [LiteratureReference:3229203] Isolation of human retinal genes: recoverin cDNA and gene [LiteratureReference:6787786] Characterization of human GRK7 as a potential cone opsin kinase [LiteratureReference:2581487] Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities [LiteratureReference:6787780] Phosphorylation of GRK7 by PKA in cone photoreceptor cells is regulated by light [LiteratureReference:6787788] Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants modified [InstanceEdit:2581512] Jassal, Bijay, 2012-11-13 [InstanceEdit:2581516] Jassal, Bijay, 2012-11-13 [InstanceEdit:2632502] Jassal, Bijay, 2012-11-21 [InstanceEdit:3223221] Jassal, Bijay, 2013-03-25 [InstanceEdit:3262437] Jassal, Bijay, 2013-04-10 [InstanceEdit:3270611] Jassal, Bijay, 2013-04-11 [InstanceEdit:3632877] Jassal, Bijay, 2013-05-28 [InstanceEdit:5205892] Jassal, Bijay, 2013-12-06 [InstanceEdit:5205897] Jassal, Bijay, 2013-12-06 [InstanceEdit:5211265] Jassal, Bijay, 2013-12-09 [InstanceEdit:5603172] Jassal, Bijay, 2014-06-30 [InstanceEdit:6787791] Jassal, Bijay, 2015-07-17 [InstanceEdit:6787804] Jassal, Bijay, 2015-07-17 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name GRK1,4,7 phosphorylate MII to p-MII output [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [EntityWithAccessionedSequence:5205903] p-S334,338,343-at-retinyl-RHO [photoreceptor disc membrane] [Homo sapiens] precedingEvent
regulatedBy [NegativeRegulation:3223247] Negative regulation by 'S-farn-GRK1:RCVRN:Ca2+ [photoreceptor disc membrane]' [NegativeRegulation:3223249] Negative regulation by 'Ca2+ [cytosol]' [NegativeRegulation:5603166] Negative regulation by 'p-MII:SAG [photoreceptor disc membrane]' releaseDate 2013-06-11 reviewed [InstanceEdit:3270610] Makino, C, 2013-04-11 reviewStatus [ReviewStatus:9821382] five stars revised [InstanceEdit:6787760] Jassal, Bijay, 2015-07-17 species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:3654536] R-HSA-2581474.4 summation [Summation:2581489] Activated rhodopsin (MII aka R*) must be deactivated to term... (hasEvent) [Pathway:2514859] Inactivation, recovery and regulation of the phototransduction cascade [Homo sapiens] (precedingEvent) [Reaction:2581488] SAG binds p-MII to form p-MII:SAG [Homo sapiens] (updatedInstance) [_UpdateTracker:9784338] Update Tracker - [Reaction:2581474] GRK1,4,7 phosphorylate MII to p-MII - v54:[addLiteratureReference, modifyText] [_UpdateTracker:9786007] Update Tracker - [Reaction:2581474] GRK1,4,7 phosphorylate MII to p-MII - v50:[addLiteratureReference, add_removeRegulator, modifyText] [_UpdateTracker:9786752] Update Tracker - [Reaction:2581474] GRK1,4,7 phosphorylate MII to p-MII - v48:[add_removeInput, add_removeOutput]
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