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Details on Person UniProt:Q8N1G0 ZNF687

Class:IdReferenceGeneProduct:257871
_chainChangeLogchain:1-1237 added on Fri February 6 2015
_displayNameUniProt:Q8N1G0 ZNF687
_timestamp2024-11-03 19:59:32
chainchain:1-1237
checksumD2DC99AA2AF44270
commentFUNCTION May be involved in transcriptional regulation.SUBUNIT Interacts with ZMYND8.INTERACTION Predominantly nuclear (PubMed:26849110). Localizes to sites of DNA damage (PubMed:27732854).ALTERNATIVE PRODUCTS Widely expressed with highest levels in obvary, muscle, blood and lung.DEVELOPMENTAL STAGE Up-regulated during osteoclastogenesis induced by treatment of peripheral blood mononuclear cells with CSF1 and TNFSF11, as well as during osteoblastogenesis.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the krueppel C2H2-type zinc-finger protein family.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Zinc finger protein 687
geneNameZNF687
KIAA1441
identifierQ8N1G0
isSequenceChangedFALSE
keywordAlternative splicing
Cytoplasm
DNA-binding
Isopeptide bond
Metal-binding
Methylation
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transcription
Transcription regulation
Ubl conjugation
Zinc
Zinc-finger
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameZNF687
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8997552] ENSEMBL:ENSG00000143373 ZNF687 [Homo sapiens]
secondaryIdentifierZN687_HUMAN
D3DV17
Q68DQ8
Q9H937
Q9P2A7
sequenceLength1237
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:257872] UniProt:Q8N1G0-2 ZNF687 [Homo sapiens]
[ReferenceIsoform:411188] UniProt:Q8N1G0-1 ZNF687 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:9940937] ZNF687 [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q8N1G0 ZNF687 (257871)