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Details on Person 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold

Class:IdBlackBoxEvent:2564826
_displayName4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold
_doReleaseTRUE
_timestamp2025-03-26 19:48:47
authored[InstanceEdit:2564829] Lill, Roland, 2012-11-07
catalystActivity[CatalystActivity:2564821] molecular adaptor activity of NDOR1:CIAPIN1 reduced [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:2564823] May, B, 2012-11-07
edited[InstanceEdit:2564820] May, B, 2012-11-07
inferredFrom
input[EntityWithAccessionedSequence:2564767] NUBP2 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:2564767] NUBP2 [cytosol] [Homo sapiens]
[Complex:2564799] NUBP1:4Fe-4S [cytosol] [Homo sapiens]
[Complex:2564799] NUBP1:4Fe-4S [cytosol] [Homo sapiens]
[SimpleEntity:71160] Fe [cytosol]
[SimpleEntity:71160] Fe [cytosol]
[SimpleEntity:71160] Fe [cytosol]
[SimpleEntity:71160] Fe [cytosol]
[SimpleEntity:2566513] S [cytosol]
[SimpleEntity:2566513] S [cytosol]
[SimpleEntity:2566513] S [cytosol]
[SimpleEntity:2566513] S [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:8952945] Glutathione-coordinated [2Fe-2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport
[LiteratureReference:2564731] Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis
modified[InstanceEdit:2566511] May, B, 2012-11-09
[InstanceEdit:3108242] May, B, 2013-02-10
[InstanceEdit:3189816] May, B, 2013-02-25
[InstanceEdit:3196191] Wu, G, 2013-02-27
[InstanceEdit:5255114] May, B, 2014-02-06
[InstanceEdit:8952957] May, Bruce, 2016-12-20
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9943301] D'Eustachio, Peter, 2025-03-26
name4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold
output[Complex:2564798] NUBP2:4Fe-4S:NUBP1 [cytosol] [Homo sapiens]
precedingEvent
regulatedBy[Requirement:8952939] Requirement by 'ABC7 dimer [mitochondrial inner membrane]'
regulationReference[RegulationReference:9641443] Requirement by 'ABC7 dimer [mitochondrial inner membrane]' Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation
releaseDate2013-03-12
reviewed[InstanceEdit:3018411] Uringa, Evert-Jan, 2013-02-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3200708] R-HSA-2564826.7
summation[Summation:2564703] A [4Fe-4S] cluster is assembled on a scaffold composed of th...
(hasEvent)[Pathway:2564830] Cytosolic iron-sulfur cluster assembly [Homo sapiens]
(precedingEvent)[BlackBoxEvent:2564828] CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775689] Update Tracker - [BlackBoxEvent:2564826] 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold - v78:[addSummation]
[_UpdateTracker:9781720] Update Tracker - [BlackBoxEvent:2564826] 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold - v60:[addRegulator, removeCatalystActivity]
[_UpdateTracker:9953682] Update Tracker - [BlackBoxEvent:2564826] 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold - v93:[addSummation, modifyText, removeLiteratureReference]
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