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Details on Person UniProt:Q96MR6 CFAP57
| Class:Id | ReferenceGeneProduct:254646 |
|---|---|
| _chainChangeLog | chain:1-1250 added on Sat February 7 2015 |
| _displayName | UniProt:Q96MR6 CFAP57 |
| _timestamp | 2025-02-21 19:16:22 |
| chain | chain:1-1250 |
| checksum | B98CB10A30D64E16 |
| comment | FUNCTION Associates with components of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility, and might act as an inner dynein arm (IDA) hub or linkage.SUBUNIT May form homodimers. Associates with components of the nexin-dynein regulatory complex (N-DRC) and the CFAP184:CFAP263 complex.SUBCELLULAR LOCATION Expressed in nasal epithelial cells.INDUCTION May be an IRF6-target.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the CFAP57 family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: fullName evidence="10"Cilia- and flagella-associated protein 57 alternativeName: fullName evidence="10"WD repeat-containing protein 65 |
| geneName | CFAP57 WDR65 |
| identifier | Q96MR6 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Disease variant Proteomics identification Reference proteome Repeat WD repeat |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | CFAP57 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997064] ENSEMBL:ENSG00000243710 CFAP57 [Homo sapiens] |
| secondaryIdentifier | CFA57_HUMAN A6NKQ3 Q17RI9 Q5TAI0 |
| sequenceLength | 1250 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8967340] UniProt:Q96MR6-1 CFAP57 [Homo sapiens] [ReferenceIsoform:8967341] UniProt:Q96MR6-2 CFAP57 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:9967064] CFAP57 [cilium] [Homo sapiens] [EntityWithAccessionedSequence:9969171] CFAP57 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q96MR6 CFAP57 (254646)
