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Details on Person Deacetylation of cohesin

Class:Id	Reaction:2545253
_displayName	Deacetylation of cohesin
_doRelease	TRUE
_timestamp	2013-02-28 10:58:06
authored	[InstanceEdit:2500295] Orlic-Milacic, M, 2012-10-02
catalystActivity	[CatalystActivity:2545204] histone deacetylase activity of HDAC8 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2545251] Orlic-Milacic, M, 2012-11-01
edited	[InstanceEdit:2555380] Matthews, L, 2012-10-05 [InstanceEdit:2555378] Gillespie, ME, 2012-10-05
input	[Complex:2484812] p-Ac-Cohesin:PDS5:WAPAL [cytosol] [Homo sapiens] [SimpleEntity:76194] CoA-SH [cytosol] [SimpleEntity:76194] CoA-SH [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:2545212] HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle
modified	[InstanceEdit:2550409] Orlic-Milacic, M, 2012-11-01 [InstanceEdit:2550416] Orlic-Milacic, M, 2012-11-01 [InstanceEdit:2555381] Orlic-Milacic, M, 2012-11-02 [InstanceEdit:3110264] Orlic-Milacic, M, 2013-02-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Deacetylation of cohesin
output	[Complex:2545249] p-Cohesin:PDS5:WAPAL [cytosol] [Homo sapiens] [SimpleEntity:76183] Ac-CoA [cytosol] [SimpleEntity:76183] Ac-CoA [cytosol]
precedingEvent	[Reaction:2467794] Resolution of sister chromatids [Homo sapiens] [Reaction:2466068] Phosphorylation of cohesin by PLK1 at chromosomal arms [Homo sapiens]
releaseDate	2012-12-04
reviewed	[InstanceEdit:2550413] Zhang, Nenggang, 2012-10-22 [InstanceEdit:3110247] Watanabe, Yoshinori, 2012-11-20 [InstanceEdit:3110251] Tanno, Yuji, 2012-11-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200584] R-HSA-2545253.2
summation	[Summation:2545250] HDAC8 deacetylates cohesin in prometaphase, after cohesin di...
(hasEvent)	[Pathway:2500257] Resolution of Sister Chromatid Cohesion [Homo sapiens]
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No pathways have been reviewed or authored by Deacetylation of cohesin (2545253)