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Details on Person Deacetylation of cleaved cohesin

Class:IdReaction:2545203
_displayNameDeacetylation of cleaved cohesin
_doReleaseTRUE
_timestamp2013-02-28 11:01:20
authored[InstanceEdit:2500295] Orlic-Milacic, M, 2012-10-02
catalystActivity[CatalystActivity:2545204] histone deacetylase activity of HDAC8 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:2545208] Orlic-Milacic, M, 2012-11-01
edited[InstanceEdit:2555380] Matthews, L, 2012-10-05
[InstanceEdit:2555378] Gillespie, ME, 2012-10-05
input[Complex:2467805] Cleaved Cohesin:PDS5:WAPAL [cytosol] [Homo sapiens]
[SimpleEntity:76194] CoA-SH [cytosol]
[SimpleEntity:76194] CoA-SH [cytosol]
[EntityWithAccessionedSequence:2484795] RAD21 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:2545212] HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle
modified[InstanceEdit:2545247] Orlic-Milacic, M, 2012-11-01
[InstanceEdit:2550409] Orlic-Milacic, M, 2012-11-01
[InstanceEdit:2550417] Orlic-Milacic, M, 2012-11-01
[InstanceEdit:2555381] Orlic-Milacic, M, 2012-11-02
[InstanceEdit:3110265] Orlic-Milacic, M, 2013-02-11
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDeacetylation of cleaved cohesin
output[EntityWithAccessionedSequence:2484802] WAPAL [cytosol] [Homo sapiens]
[DefinedSet:2484796] PDS5 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:2484901] RAD21(1-172) [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:2500308] RAD21(173-450) [cytosol] [Homo sapiens]
[SimpleEntity:76183] Ac-CoA [cytosol]
[SimpleEntity:76183] Ac-CoA [cytosol]
[EntityWithAccessionedSequence:2500309] p-S454-RAD21(451-631) [cytosol] [Homo sapiens]
[Complex:2545214] Cohesin Complex [cytosol] [Homo sapiens]
precedingEvent
releaseDate2012-12-04
reviewed[InstanceEdit:2550413] Zhang, Nenggang, 2012-10-22
[InstanceEdit:3110247] Watanabe, Yoshinori, 2012-11-20
[InstanceEdit:3110251] Tanno, Yuji, 2012-11-20
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3200728] R-HSA-2545203.2
summation[Summation:2545246] Histone deacetylase HDAC8 deacetylates SMC3 cohesin subunit....
(hasEvent)[Pathway:2467813] Separation of Sister Chromatids [Homo sapiens]
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No pathways have been reviewed or authored by Deacetylation of cleaved cohesin (2545203)