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Details on Person UniProt:Q9H832 UBE2Z
| Class:Id | ReferenceGeneProduct:253545 |
|---|---|
| _chainChangeLog | chain:1-354 added on Sat February 7 2015 |
| _displayName | UniProt:Q9H832 UBE2Z |
| _timestamp | 2024-11-03 19:44:05 |
| chain | chain:1-354 |
| checksum | 5AFC148BD8D31356 |
| comment | FUNCTION Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.CATALYTIC ACTIVITY S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PATHWAY Protein modification; protein ubiquitination.INTERACTION Widely expressed. Highly in placenta, pancreas, spleen and testis.SIMILARITY Belongs to the ubiquitin-conjugating enzyme family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Ubiquitin-conjugating enzyme E2 Z ecNumber: 2.3.2.23 alternativeName: E2 ubiquitin-conjugating enzyme Z alternativeName: Uba6-specific E2 conjugating enzyme 1 shortName: Use1 alternativeName: Ubiquitin carrier protein Z alternativeName: Ubiquitin-protein ligase Z |
| geneName | UBE2Z HOYS7 |
| identifier | Q9H832 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Apoptosis ATP-binding Cytoplasm Nucleotide-binding Nucleus Phosphoprotein Proteomics identification Reference proteome Transferase Ubl conjugation pathway |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | UBE2Z |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962176] ENSEMBL:ENSG00000159202 UBE2Z [Homo sapiens] |
| secondaryIdentifier | UBE2Z_HUMAN A6N8M6 A6NC60 Q7L354 Q8TCM4 Q9H893 |
| sequenceLength | 354 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:253546] UniProt:Q9H832-2 UBE2Z [Homo sapiens] [ReferenceIsoform:414319] UniProt:Q9H832-1 UBE2Z [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:947616] UBE2Z [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:8852091] UBE2Z [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8864147] Ub-C188-UBE2Z [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8864182] Ub-C188-UBE2Z [cytosol] [Homo sapiens] |
| (referenceSequence) | [ModifiedResidue:8864183] S-(glycyl)-L-cysteine (Cys-Gly) at 188 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9H832 UBE2Z (253545)
