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Details on Person Nckx1 exchanges Na+ for Ca2+/K+

Class:Id	Reaction:2534148
_displayName	Nckx1 exchanges Na+ for Ca2+/K+
_doRelease	TRUE
_timestamp	2013-08-30 17:44:09
authored	[InstanceEdit:2534149] Jassal, B, 2012-10-24
catalystActivity	[CatalystActivity:4420238] calcium, potassium:sodium antiporter activity of Slc24a1 [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:2534149] Jassal, B, 2012-10-24
edited	[InstanceEdit:2534149] Jassal, B, 2012-10-24
input	[SimpleEntity:74016] Ca2+ [cytosol] [SimpleEntity:29804] K+ [cytosol] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:74392] Na+-Ca2+ exchange in bovine rod outer segments requires and transports K+. [LiteratureReference:2534146] Identification of the sodium-calcium exchanger as the major ricin-binding glycoprotein of bovine rod outer segments and its localization to the plasma membrane [LiteratureReference:74321] Extrusion of calcium from rod outer segments is driven by both sodium and potassium gradients. [LiteratureReference:74120] The Na/Ca-K exchanger of rod photoreceptor exists as dimer in the plasma membrane. [LiteratureReference:3262447] Binding of the cGMP-gated channel to the Na/Ca-K exchanger in rod photoreceptors
modified	[InstanceEdit:2796105] Jassal, Bijay, 2012-12-11 [InstanceEdit:3223221] Jassal, Bijay, 2013-03-25 [InstanceEdit:3262437] Jassal, Bijay, 2013-04-10 [InstanceEdit:3632874] Jassal, Bijay, 2013-05-28 [InstanceEdit:4420236] Jassal, B, 2013-08-30 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Nckx1 exchanges Na+ for Ca2+/K+ Slc24a1 exchanges Na+ for Ca2+/K+
output	[SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74126] K+ [extracellular region] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:83910] Na+ [cytosol]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3270610] Makino, C, 2013-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48898] Bos taurus
stableIdentifier	[StableIdentifier:3654422] R-BTA-2534148.2
summation	[Summation:2534144] The sodium/potassium/calcium exchanger 1 (NCKX1, encoded by ...
(inferredFrom)	[Reaction:2514891] SLC24A1 exchanges 4Na+ for Ca2+, K+ [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787078] Update Tracker - [Reaction:2534148] Nckx1 exchanges Na+ for Ca2+/K+ - v46:[add_removeCatalystActivity]
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No pathways have been reviewed or authored by Nckx1 exchanges Na+ for Ca2+/K+ (2534148)