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Details on Person iC3b proteolysis

Class:Id	BlackBoxEvent:2530565
_displayName	iC3b proteolysis
_doRelease	TRUE
_timestamp	2014-11-20 02:48:23
authored	[InstanceEdit:2869458] Shamovsky, V, 2012-12-20
catalystActivity	[CatalystActivity:2132268] serine-type endopeptidase activity of CFI [extracellular region]
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:2530587] Shamovsky, V, 2012-10-17
edited	[InstanceEdit:5149549] Shamovsky, V, 2013-11-19
input	[Complex:2867942] iC3b [plasma membrane] [Gallus gallus]
isChimeric	FALSE
literatureReference	[LiteratureReference:2530560] Cloning of a gene fragment encoding chicken complement component C3d with expression and immunogenicity of Newcastle disease virus F gene-C3d fusion protein [LiteratureReference:2867934] Unique structure of iC3b resolved at a resolution of 24 � by 3D-electron microscopy
modified	[InstanceEdit:2867949] Shamovsky, V, 2012-12-19 [InstanceEdit:3009248] Shamovsky, V, 2013-02-05 [InstanceEdit:3465608] Shamovsky, V, 2013-05-17 [InstanceEdit:3632869] Shamovsky, V, 2013-05-28 [InstanceEdit:3632870] Shamovsky, V, 2013-05-28 [InstanceEdit:5083130] Shamovsky, V, 2013-11-05 [InstanceEdit:5149551] Matthews, L, 2013-11-20 [InstanceEdit:5324712] Shamovsky, V, 2014-02-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	iC3b proteolysis
output	[Complex:2867943] C3c [extracellular region] [Gallus gallus] [Complex:2867941] C3dg [plasma membrane] [Gallus gallus]
precedingEvent	[Reaction:2132276] Complement factor I inactivates C3b [Gallus gallus] [Reaction:2132261] Complement factor H binds to C3b [Gallus gallus]
releaseDate	2014-03-12
reviewed	[InstanceEdit:2562608] D'Eustachio, P, 2012-11-06 [InstanceEdit:3006589] Jupe, S, 2013-01-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:5644855] R-GGA-2530565.2
summation	[Summation:2530548] In mammals, inactivated C3b (iC3b) undergoes proteolytic cle...
(hasEvent)	[Pathway:2132281] Regulation of complement cascades [Gallus gallus]
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No pathways have been reviewed or authored by iC3b proteolysis (2530565)