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Details on Person cGMP dissociates from CNG channels

Class:Id	Reaction:2514865
_displayName	cGMP dissociates from CNG channels
_doRelease	TRUE
_timestamp	2013-05-31 09:46:11
authored	[InstanceEdit:2514885] Jassal, B, 2012-10-11
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:2514885] Jassal, B, 2012-10-11
edited	[InstanceEdit:2514885] Jassal, B, 2012-10-11
input	[Complex:74011] cGMP:CNG channel [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3223235] A new subunit of the cyclic nucleotide-gated cation channel in retinal rods [LiteratureReference:74310] Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression. [LiteratureReference:3222188] Amplification and kinetics of the activation steps in phototransduction [LiteratureReference:2796098] Cyclic GMP-activated conductance of retinal photoreceptor cells
modified	[InstanceEdit:2648981] Jassal, Bijay, 2012-11-22 [InstanceEdit:2649000] Jassal, Bijay, 2012-11-23 [InstanceEdit:2796105] Jassal, Bijay, 2012-12-11 [InstanceEdit:3223221] Jassal, Bijay, 2013-03-25 [InstanceEdit:3262437] Jassal, Bijay, 2013-04-10 [InstanceEdit:3270611] Jassal, Bijay, 2013-04-11 [InstanceEdit:3632877] Jassal, Bijay, 2013-05-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	cGMP dissociates from CNG channels Decreased cGMP closes cation channels
output	[Complex:74001] CNG channel [plasma membrane] [Homo sapiens] [SimpleEntity:30991] cGMP [cytosol]
precedingEvent	[Reaction:74059] PDE6 hydrolyses cGMP to GMP [Homo sapiens] [Reaction:74065] GNAT1-GTP binds PDE6 and activates it [Homo sapiens]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3270610] Makino, C, 2013-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654438] R-HSA-2514865.2
summation	[Summation:2514905] As cGMP is hydrolysed during the activation phase of phototr...
(hasEvent)	[Pathway:2485179] Activation of the phototransduction cascade [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9786762] Update Tracker - [Reaction:2514865] cGMP dissociates from CNG channels - v48:[removeRegulator]
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No pathways have been reviewed or authored by cGMP dissociates from CNG channels (2514865)