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Query author contributions in Reactome

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Details on Person UniProt:O75602 SPAG6

Class:IdReferenceGeneProduct:248970
_chainChangeLogchain:1-509 added on Fri February 6 2015
_displayNameUniProt:O75602 SPAG6
_timestamp2024-08-09 18:56:55
chainchain:1-509
checksum03D868E31D3883E1
commentFUNCTION Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.SUBUNIT Interacts with SPAG16 and SPAG17.SUBCELLULAR LOCATION Associated with microtubules. Detected on the sperm flagellum (PubMed:10493827). Localizes in the cilium axoneme in a SPEF1-dependent manner (By similarity).ALTERNATIVE PRODUCTS Highly expressed in testis.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Sperm-associated antigen 6 alternativeName: Protein PF16 homolog alternativeName: Repro-SA-1 alternativeName: Sperm flagellar protein
geneNameSPAG6
PF16
identifierO75602
isSequenceChangedFALSE
keywordAlternative splicing
Cell projection
Cilium
Cilium biogenesis/degradation
Cytoplasm
Cytoskeleton
Flagellum
Microtubule
Proteomics identification
Reference proteome
Repeat
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
nameSPAG6
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8996282] ENSEMBL:ENSG00000077327 SPAG6 [Homo sapiens]
secondaryIdentifierSPAG6_HUMAN
A8K1I8
B4DXZ4
Q5VUX5
Q5VUX6
Q5VUX7
Q6FI74
Q8NHQ6
sequenceLength509
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:248971] UniProt:O75602-2 SPAG6 [Homo sapiens]
[ReferenceIsoform:248972] UniProt:O75602-3 SPAG6 [Homo sapiens]
[ReferenceIsoform:248973] UniProt:O75602-4 SPAG6 [Homo sapiens]
[ReferenceIsoform:401873] UniProt:O75602-1 SPAG6 [Homo sapiens]
[ReferenceIsoform:8968064] UniProt:O75602-5 SPAG6 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:9966928] SPAG6 [cilium] [Homo sapiens]
[EntityWithAccessionedSequence:9969404] SPAG6 [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:O75602 SPAG6 (248970)