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Details on Person UniProt:Q9NQZ2 UTP3
| Class:Id | ReferenceGeneProduct:247473 |
|---|---|
| _chainChangeLog | chain:1-479 added on Fri February 6 2015 |
| _displayName | UniProt:Q9NQZ2 UTP3 |
| _timestamp | 2024-11-03 20:03:06 |
| chain | chain:1-479 |
| checksum | B4A842785342766D |
| comment | FUNCTION Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.INTERACTION Citrullinated by PADI4.SIMILARITY Belongs to the SAS10 family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Something about silencing protein 10 alternativeName: Charged amino acid-rich leucine zipper 1 shortName: CRL1 alternativeName: Disrupter of silencing SAS10 alternativeName: UTP3 homolog |
| geneName | UTP3 CRLZ1 SAS10 |
| identifier | Q9NQZ2 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Chromatin regulator Citrullination Developmental protein Isopeptide bond Methylation Nucleus Phosphoprotein Proteomics identification Reference proteome Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | UTP3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962411] ENSEMBL:ENSG00000132467 UTP3 [Homo sapiens] |
| secondaryIdentifier | SAS10_HUMAN Q6FI82 |
| sequenceLength | 479 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:6790637] UTP3 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9NQZ2 UTP3 (247473)
