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Details on Person FSTL3 binds Activin

Class:Id	Reaction:2473186
_displayName	FSTL3 binds Activin
_doRelease	TRUE
_timestamp	2016-02-18 15:12:53
authored	[InstanceEdit:2473163] May, B, 2012-09-21
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2473197] May, B, 2012-09-21
edited	[InstanceEdit:2473163] May, B, 2012-09-21
input	[DefinedSet:2470494] Activin A,AB,B [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:2473199] FSTL3 [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:2473199] FSTL3 [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2473179] Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG) [LiteratureReference:2473214] Follistatin-related protein and follistatin differentially neutralize endogenous vs. exogenous activin [LiteratureReference:2473210] The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity [LiteratureReference:2473207] Human follistatin-related protein: a structural homologue of follistatin with nuclear localization
modified	[InstanceEdit:2559592] May, B, 2012-11-02 [InstanceEdit:2584313] May, B, 2012-11-14 [InstanceEdit:8858361] Jupe, Steve, 2016-02-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FSTL3 binds Activin
output	[Complex:2473219] Activin A,AB,B:FSTL3 [extracellular region] [Homo sapiens]
releaseDate	2012-12-04
reviewed	[InstanceEdit:2584311] Chen, Ye-Guang, 2012-11-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200374] R-HSA-2473186.3
summation	[Summation:2473198] Two molecules of FSTL3 bind an Activin dimer (Sidis et al. 2...
(hasEvent)	[Pathway:2473224] Antagonism of Activin by Follistatin [Homo sapiens]
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No pathways have been reviewed or authored by FSTL3 binds Activin (2473186)