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Details on Person Acvr2a phosphorylates Acvr1c in response to Activin

Class:Id	Reaction:2470487
_displayName	Acvr2a phosphorylates Acvr1c in response to Activin
_doRelease	TRUE
_timestamp	2014-02-03 18:44:55
authored	[InstanceEdit:2470497] May, B, 2012-09-13
catalystActivity	[CatalystActivity:2470492] protein serine/threonine kinase activity of Activin AB,B:Acvr2a:Acvr1c [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:2470496] May, B, 2012-09-18
edited	[InstanceEdit:2470497] May, B, 2012-09-13
input	[SimpleEntity:113592] ATP [cytosol] [Complex:2470470] Activin AB,B:Acvr2a:Acvr1c [plasma membrane] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:2470488] Activin isoforms signal through type I receptor serine/threonine kinase ALK7 [LiteratureReference:2584307] Activin B can signal through both ALK4 and ALK7 in gonadotrope cells
modified	[InstanceEdit:2584310] May, B, 2012-11-14 [InstanceEdit:2584313] May, B, 2012-11-14 [InstanceEdit:5251385] May, B, 2014-02-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Acvr2a phosphorylates Acvr1c in response to Activin
output	[SimpleEntity:29370] ADP [cytosol] [Complex:2470481] Activin AB,B:Acvr2a:p-Acvr1c [plasma membrane] [Mus musculus]
precedingEvent	[Reaction:2470495] Activin AB/B binds Activin Receptor Acvr2a:Acvr1c [Mus musculus]
releaseDate	2012-12-04
reviewed	[InstanceEdit:2584311] Chen, Ye-Guang, 2012-11-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:3200474] R-MMU-2470487.2
summation	[Summation:2470486] Binding of Activin AB or Activin B to the type II receptor A...
(inferredFrom)	[Reaction:2470508] ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin [Homo sapiens]
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No pathways have been reviewed or authored by Acvr2a phosphorylates Acvr1c in response to Activin (2470487)