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Details on Person UniProt:Q9HBX9-4 RXFP1
| Class:Id | ReferenceIsoform:246836 |
|---|---|
| _chainChangeLog | chain:1-757 added on Fri February 6 2015 |
| _displayName | UniProt:Q9HBX9-4 RXFP1 |
| _timestamp | 2024-11-03 20:11:56 |
| chain | chain:1-757 |
| checksum | B32DD71B1A5D5864 |
| comment | FUNCTION Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.SUBUNIT Interacts with C1QTNF8.INTERACTION Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.SIMILARITY Belongs to the G-protein coupled receptor 1 family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Relaxin receptor 1 alternativeName: Leucine-rich repeat-containing G-protein coupled receptor 7 alternativeName: Relaxin family peptide receptor 1 |
| geneName | RXFP1 LGR7 |
| identifier | Q9HBX9 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Calcium Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Leucine-rich repeat Membrane Metal-binding Proteomics identification Receptor Reference proteome Repeat Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | RXFP1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9002032] ENSEMBL:ENSG00000171509 RXFP1 [Homo sapiens] |
| secondaryIdentifier | RXFP1_HUMAN B4DHD1 B4DTV2 Q2M215 Q3KU24 Q3KU25 Q3KU26 |
| sequenceLength | 757 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q9HBX9-4 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9HBX9-4 RXFP1 (246836)
