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Details on Person AGRN binds Beta amyloid fibril via GAG chains

Class:Id	Reaction:2467665
_displayName	AGRN binds Beta amyloid fibril via GAG chains
_doRelease	TRUE
_timestamp	2013-05-31 09:44:05
authored	[InstanceEdit:2976617] Jupe, S, 2013-01-10
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2467678] Jupe, S, 2012-09-13
edited	[InstanceEdit:3318356] Jupe, S, 2013-04-26
input	[EntityWithAccessionedSequence:375056] AGRN(30-2068) [extracellular region] [Homo sapiens] [Polymer:976748] Beta amyloid fibril [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2467682] Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brain [LiteratureReference:2467679] Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchyma
modified	[InstanceEdit:2681745] Jupe, S, 2012-11-28 [InstanceEdit:2796108] Jupe, S, 2012-12-11 [InstanceEdit:3446769] Jupe, S, 2013-05-15 [InstanceEdit:3597637] Jupe, S, 2013-05-22 [InstanceEdit:3597718] Jupe, S, 2013-05-22 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AGRN binds Beta amyloid fibril via GAG chains
output	[Complex:2467662] AGRN:Beta amyloid fibril [extracellular region] [Homo sapiens]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3597636] Narayanan, Venkatesan, 2013-05-21 [InstanceEdit:3597676] Ricard-Blum, Sylvie, 2013-05-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654387] R-HSA-2467665.2
summation	[Summation:2467672] Several agrin (AGRN) ligands require the presence of heparan...
(hasEvent)	[Pathway:3000178] ECM proteoglycans [Homo sapiens]
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No pathways have been reviewed or authored by AGRN binds Beta amyloid fibril via GAG chains (2467665)