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Details on Person Biglycan is a member of the small leucine-rich repeat proteo...

Class:IdSummation:2466193
_displayNameBiglycan is a member of the small leucine-rich repeat proteo...
_timestamp2012-09-06 14:56:51
created[InstanceEdit:2466194] Jupe, S, 2012-09-06
literatureReference[LiteratureReference:2466236] Interaction of biglycan with type I collagen
[LiteratureReference:2466199] The interactions of cartilage proteoglycans with collagens are determined by their structures
[LiteratureReference:2466165] Biglycan and decorin bind close to the n-terminal region of the collagen VI triple helix
[LiteratureReference:2466201] Interactions between collagen IX and biglycan measured by atomic force microscopy
[LiteratureReference:2466190] Influence of collagen-fibril-based coatings containing decorin and biglycan on osteoblast behavior
textBiglycan is a member of the small leucine-rich repeat proteoglycan (SLRP) family, which also includes decorin, fibromodulin (Hedlund et al. 1994 - binding to collagen II), lumican and asporin (Hedbom & Heinegard 1993, Ezura et al. 2000). All appear to be involved in collagen fibril formation and matrix assembly (Ameye & Young 2002). Biglycan binds collagen types I (Schönherr et al. 1995), II (Bovine, using pig byglycan - Vynios et al. 2001, Bovine, using bovine biglycan - Douglas et al. 2008), III (Bovine, using bovine biglycan - Douglas et al. 2008), VI (Wiberg et al. 2001) and IX (Chen et al. 2006 - species source of collagen/biglycan unknown).
(summation)[Reaction:2466177] BGN binds Collagen types II, III, IV [Bos taurus]
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