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Details on Person UniProt:Q2TBI6 MRPL32
| Class:Id | ReferenceGeneProduct:245971 |
|---|---|
| _chainChangeLog | transit peptide:1- added on Fri February 6 2015;chain:-188 added on Fri February 6 2015 |
| _displayName | UniProt:Q2TBI6 MRPL32 |
| _timestamp | 2024-08-09 19:24:47 |
| chain | transit peptide:1- chain:-188 |
| checksum | 616D69398EA34ABA |
| comment | FUNCTION Component of the mitochondrial large ribosomal subunit (mt-LSU). The mitochondrial ribosome (mitoribosome) is a large ribonucleoprotein complex responsible for the synthesis of proteins inside mitochondria.SUBUNIT Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.SUBCELLULAR LOCATION MRPL32 precursor is processed by the m-AAA protease (composed of AFG3L2 and SPG7), which cleaves the N-terminal transit peptide (By similarity). Cleavage by the m-AAA protease takes place prior to assembly into the large subunit, an essential step for mitochondrial ribosome (mitoribosome) assembly (By similarity). Proper processing by the m-AAA protease is dependent on the zinc-binding region within the tightly folded C-terminal domain of MRPL32: zinc-dependent folding halts degradation initiated from the N-terminus and triggers the release of mature MRPL32 (By similarity).SIMILARITY Belongs to the bacterial ribosomal protein bL32 family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: fullName evidence="7"Large ribosomal subunit protein bL32m alternativeName: 39S ribosomal protein L32, mitochondrial shortName: L32mt shortName: MRP-L32 |
| geneName | MRPL32 |
| identifier | Q2TBI6 |
| isSequenceChanged | FALSE |
| keyword | Direct protein sequencing Metal-binding Mitochondrion Reference proteome Ribonucleoprotein Ribosomal protein Transit peptide Zinc |
| modified | [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8964659] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 |
| name | MRPL32 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | RM32_BOVIN |
| sequenceLength | 188 |
| species | [Species:48898] Bos taurus |
| (referenceEntity) | [EntityWithAccessionedSequence:5432399] MRPL32 [mitochondrial inner membrane] [Bos taurus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q2TBI6 MRPL32 (245971)
