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Details on Person UniProt:F1MV99 SSTR5

Class:IdReferenceGeneProduct:2455460
_chainChangeLogchain:1-368 added on Sat February 7 2015
_displayNameUniProt:F1MV99 SSTR5
_timestamp2023-11-03 17:34:45
chainchain:1-368
checksum3F21C39B939F3BF8
commentFUNCTION Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization (By similarity).SUBUNIT Heterodimer with SSTR2. Heterodimerization with SSTR2 increases cell growth inhibition activity of SSTR2 (By similarity).SUBCELLULAR LOCATION Palmitoylated by ZDHHC5, but not ZDHHC3, nor ZDHHC8. Palmitoylation creates an additional intracellular loop which is thought to be important for efficient coupling to G-proteins and may target the protein to lipid rafts (By similarity).SIMILARITY Belongs to the G-protein coupled receptor 1 family.
created[InstanceEdit:2455454] Weiser, JD
descriptionrecommendedName: Somatostatin receptor type 5 shortName: SS-5-R shortName: SS5-R shortName: SS5R
geneNameSSTR5
identifierF1MV99
isSequenceChangedFALSE
keywordCell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Lipoprotein
Membrane
Palmitate
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix
modified[InstanceEdit:3445779] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9657908] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameSSTR5
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierSSR5_BOVIN
sequenceLength368
species[Species:48898] Bos taurus
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No pathways have been reviewed or authored by UniProt:F1MV99 SSTR5 (2455460)