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Details on Person UniProt:E9QA28 Ceacam16
| Class:Id | ReferenceGeneProduct:2455456 |
|---|---|
| _chainChangeLog | signal peptide:1-22 added on Fri February 6 2015;chain:23-426 added on Fri February 6 2015 |
| _displayName | UniProt:E9QA28 Ceacam16 |
| _timestamp | 2025-02-21 18:45:08 |
| chain | signal peptide:1-22 chain:23-426 |
| checksum | B2A348370AB0AB46 |
| comment | FUNCTION Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.SUBUNIT Homooligomer; can for homodimers and homotetramers (By similarity). Interacts with TECTA and TECTB (PubMed:25080593).SUBCELLULAR LOCATION Localizes at the tip of cochlear outer hair cells and to the tectorial membrane.TISSUE SPECIFICITY Expressed in cochlear outer hair cells (OHC).DEVELOPMENTAL STAGE Abundantly expressed in cochleae from embryonic day 17 to postnatal day 42.DISRUPTION PHENOTYPE Mutant mice show loss of striated-sheet matrix and Hensen's stripe, a prominent feature in the basal two-thirds of the tectorial membrane. They have enhanced spontaneous, stimulus-frequency, and transiently evoked otoacoustic emissions.SIMILARITY Belongs to the immunoglobulin superfamily. CEA family. |
| created | [InstanceEdit:2455454] Weiser, JD |
| description | recommendedName: fullName evidence="7"Cell adhesion molecule CEACAM16 alternativeName: Carcinoembryonic antigen-related cell adhesion molecule 16 shortName evidence="8"CEA cell adhesion molecule 16 |
| geneName | Ceacam16 |
| identifier | E9QA28 |
| isSequenceChanged | FALSE |
| keyword | Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Repeat Secreted Signal |
| modified | [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618410] Weiser, JD [InstanceEdit:5618413] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9666080] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | Ceacam16 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | CEA16_MOUSE B2RUD6 |
| sequenceLength | 426 |
| species | [Species:48892] Mus musculus |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:E9QA28 Ceacam16 (2455456)
